Evidence map›Paper›PMID 31489065›Full record

ArticleThe Pan African medical journal2019

Association between highly active antiretroviral therapy (HAART) and hypertension in persons living with HIV/AIDS at the Bamenda regional hospital, Cameroon.

Pepanze Jill Pangmekeh, Mbunka Muhamed Awolu, Simo Gustave, Tayong Gladys, Samuel Nambile Cumber

Open access · goldAbstract read
In one paragraph

Article in The Pan African medical journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Salt Taste and Salt Sensitive Hypertension in HIV.Current hypertension reports · 2023
    Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. HIV Associated Preeclampsia: A Multifactorial Appraisal.International journal of molecular sciences · 2021
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 3 countries.

Pepanze Jill PangmekehUniversity of Dschang, Department of Biomedical Sciences, Dschang, Cameroon.
Mbunka Muhamed AwoluUniversity of Dschang, Department of Biomedical Sciences, Dschang, Cameroon.
Simo GustaveUniversity of Dschang, Department of Biomedical Sciences, Dschang, Cameroon.
Tayong GladysRegional Coordinator For the Fight Against HIV/AIDS North West Region, Bamenda, Cameroon.
Samuel Nambile CumberFaculty of Health Sciences, University of the Free State, Bloemfontein, South Africa.
Université de Dschang · CMUniversity of the Free State · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe introduction of highly active antiretroviral therapy (HAART) in the treatment of HIV infection has provided different good results: like long-term viral suppression, the decrease of opportunistic infections, and repair of the immune system.

methodsWe carried out a hospital-based cross-sectional analytic study involving 315 participants 228 were on HAART (group 1) and 87 were HAART-naïve (group 2) at the HIV treatment centre of the Bamenda regional hospital with our study population being all people living with HIV (PLWHIV) in the North West region of Cameroon. The sampling was performed from the 15

resultsThe prevalence of hypertension in the HAART group was 36.44% (n=82, CI: 30.15%-43.10%) compared to that of the HAART-naïve group which was 13.33% (n=12, CI: 7.08%-22.13%, P=0.01). HAART was associated with HTN after controlling for gender, family history of hypertension, body mass index (BMI), smoking and alcohol consumption. The odds ratio of the HAART-treated versus the HAART-naïve was 3.86 (95% CI: 1.98-7.50). We also found an association between TDF/3TC/EFV (OR=2.83), AZT/3TC/NVP (OR=2.82), AZT/3TC+EFV (OR=3.48) and TDF/3TC+NVP (OR=2.36) and HTN whereas those on AZT+3TC+ATV/r (OR=0.84) and TDF+3TC+ATV/r (OR=0.45) were not associated to hypertension.

conclusionOur result suggests that blood pressure should be periodically measured and treated when necessary in PLWHIV on HAART.

Indexed as

Acquired Immunodeficiency SyndromeAdultAgedAnti-HIV AgentsAntiretroviral Therapy, Highly ActiveBlood PressureCameroonCross-Sectional StudiesFemaleHIV InfectionsHumansHypertensionMaleMiddle AgedPrevalenceSurveys and QuestionnairesAnti-HIV AgentsassociationHAARTHAART-naïveHypertensionPLWHIV

Identifiers

PMID31489065
PMCPMC6713512
OpenAlexW2978805855

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.