ArticleNature communications2019
Evidence for allocentric boundary and goal direction information in the human entorhinal cortex and subiculum.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Trial
- Encoding Patterned Spatial Behavior in the Subiculum.Hippocampus · 2026Review
- Egocentric Dominance in Spatial Representations: The Role of Environmental Familiarity in Building Cognitive Maps.Brain and behavior · 2026Article
- Egocentric Spatial Memory Deficit in Amnestic Mild Cognitive Impairment Revealed Through Virtual Reality: Cross-Sectional Study.JMIR aging · 2026Article
- Article
- Representational similarity analysis reveals cue-independent spatial representations for landmarks and self-motion cues in human retrosplenial cortex.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Spatial navigation questionnaires as a supportive diagnostic tool in early Alzheimer's disease.iScience · 2024Article
- Article
- Hippocampal subfields and their neocortical interactions during autobiographical memory.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- The format of the cognitive map depends on the structure of the environment.Journal of experimental psychology. General · 2024Article
- Disentangling reference frames in the neural compass.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Neural representation of goal direction in the monarch butterfly brain.Nature communications · 2023Article
- Task-related connectivity of decision points during spatial navigation in a schematic map.Brain structure & function · 2022Article
- Microcircuits for spatial coding in the medial entorhinal cortex.Physiological reviews · 2022Review
- The Geometric World of Fishes: A Synthesis on Spatial Reorientation in Teleosts.Animals : an open access journal from MDPI · 2022Review
- Cue combination in goal-oriented navigation.Quarterly journal of experimental psychology (2006) · 2021Article
- Increased Hippocampal Excitability and Altered Learning Dynamics Mediate Cognitive Mapping Deficits in Human Aging.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Homologous laminar organization of the mouse and human subiculum.Scientific reports · 2021Article
- Structuring Knowledge with Cognitive Maps and Cognitive Graphs.Trends in cognitive sciences · 2021Review
- Article
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4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
In rodents, cells in the medial entorhinal cortex (EC) and subiculum code for the allocentric direction to environment boundaries, which is an important prerequisite for accurate positional coding. Although in humans boundary-related signals have been reported, there is no evidence that they contain allocentric direction information. Furthermore, it has not been possible to separate boundary versus goal direction signals in the EC/subiculum. Here, to address these questions, we had participants learn a virtual environment containing four unique boundaries. Participants then underwent fMRI scanning where they made judgements about the allocentric direction of a cue object. Using multivariate decoding, we found information regarding allocentric boundary direction in posterior EC and subiculum, whereas allocentric goal direction was decodable from anterior EC and subiculum. These data provide the first evidence of allocentric boundary coding in humans, and are consistent with recent conceptualisations of a division of labour within the EC.
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