Evidence map›Paper›PMID 31488711›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Inside-out signaling through FAK-integrin axis may regulate circulating cancer cell metastatic adhesion.

Christina Downey-Biechler, David H Craig, Shyam K More, Marc D Basson

Open access · bronzeAbstract readLetterComment
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Modulation of the Mechanosensory Matrisome by Serotonergic Signaling.Results and problems in cell differentiation · 2026
    Review
  3. Review
  4. Article
  5. Extracellular matrix and its therapeutic potential for cancer treatment.Signal transduction and targeted therapy · 2021
    Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Christina Downey-BiechlerDepartment of Family Medicine, Ascension Hospital System Providence, Southfield, MI 48075.
David H CraigDepartment of Surgery, University of North Dakota School of Medicine and Health Sciences, Grand Forks, ND 58202.
Shyam K MoreDepartment of Surgery, University of North Dakota School of Medicine and Health Sciences, Grand Forks, ND 58202.
Marc D BassonDepartment of Surgery, University of North Dakota School of Medicine and Health Sciences, Grand Forks, ND 58202 marc.basson@und.edu.ORCID 0000-0001-9696-2789
University of North Dakota · USProvidence College · US

Funding

Tracking and Evaluation CoreU54GM128729 · NIGMS · UNIVERSITY OF NORTH DAKOTA · PI BASSON, MARC D. · 2018 to 2022
$20.3M
Pressure-stimulated cell adhesionR01DK060771 · NIDDK · WAYNE STATE UNIVERSITY · PI BASSON, MARC D. · 2001 to 2009
$2.7M
NIDDK NIH HHS R01 DK060771NIGMS NIH HHS U54 GM128729
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

IntegrinsSignal TransductionCell AdhesionIntegrins

Identifiers

PMID31488711
PMCPMC6778248
OpenAlexW2971901531

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.