Evidence map›Paper›PMID 31488605›Full record

ArticleOccupational and environmental medicine2019

Multicohort study of change in job strain, poor mental health and incident cardiometabolic disease.

Linda L Magnusson Hanson, Naja Hulvej Rod, Jussi Vahtera, Paraskevi Peristera, Jaana Pentti, Reiner Rugulies, Ida Elisabeth Huitfeldt Madsen, Anthony D LaMontagne, Allison Milner, Theis Lange and 5 more

Open access · hybridAbstract read
In one paragraph

Article in Occupational and environmental medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
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  4. Article
  5. Article
  6. On the Biopsychosocial Costs of Alienated Labor.Work, employment & society : a journal of the British Sociological Association · 2021
    Article
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  8. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 5 countries.

Linda L Magnusson HansonStress Research Institute, Stockholm University, Stockholm, Sweden linda.hanson@su.se.
Naja Hulvej RodSection of Epidemiology, Department of Public Health, University of Copenhagen, Social Medicine Section, Copenhagen, Denmark.
Jussi VahteraDepartment of Public Health, University of Turku, Turku, Finland.ORCID 0000-0002-6036-061X
Paraskevi PeristeraStress Research Institute, Stockholm University, Stockholm, Sweden.
Jaana PenttiDepartment of Public Health, University of Turku, Turku, Finland.
Reiner RuguliesSection of Epidemiology, Department of Public Health, University of Copenhagen, Social Medicine Section, Copenhagen, Denmark.
Ida Elisabeth Huitfeldt MadsenNational Research Centre for the Working Environment, Copenhagen, Denmark.
Anthony D LaMontagneMcCaughey Centre, Centre for Health Equity, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia.ORCID 0000-0002-5811-5906
Allison MilnerDisability and Health Unit, Centre for Health Equity, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia.ORCID 0000-0003-4657-0503
Theis LangeSection of Biostatistics, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Sakari SuominenDepartment of Public Health, University of Turku, Turku, Finland.
Sari StenholmDepartment of Public Health, University of Turku, Turku, Finland.ORCID 0000-0001-7560-0930
Tianwei XuSection of Epidemiology, Department of Public Health, University of Copenhagen, Social Medicine Section, Copenhagen, Denmark.
Mika KivimäkiClinicum, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Hugo WesterlundStress Research Institute, Stockholm University, Stockholm, Sweden.
University of Copenhagen · DKUniversity of Turku · FIStockholm University · SEDeakin University · AUNational Research Centre for the Working Environment · DKThe University of Melbourne · AUUniversity of Helsinki · FI

Funding

Socio-economic status and heterogeneity in agingR01AG013196 · NIA · UNIVERSITY OF LONDON INST OF NEUROLOGY · PI MARMOT, MICHAEL G, SINGH-MANOUX, ARCHANA · 1996 to 2013
$3.5M
Socioeconomic gradient in CHD in early old ageR01HL036310 · NHLBI · UNIVERSITY OF LONDON · PI KIVIMAKI, MIKA J, MARMOT, MICHAEL G · 1986 to 2012
$3.1M
British Heart Foundation RG/16/11/32334Medical Research Council K013351Medical Research Council MR/K013351/1Medical Research Council MR/R024227/1Medical Research Council MR/S011676/1NHLBI NIH HHS R01 HL036310NIA NIH HHS R01 AG013196
6 · The paper itself

Abstract

objectivesSeveral recent large-scale studies have indicated a prospective association between job strain and coronary heart disease, stroke and diabetes. Job strain is also associated with poorer mental health, a risk factor for cardiometabolic disease. This study investigates the prospective relationships between change in job strain, poor mental health and cardiometabolic disease, and whether poor mental health is a potential mediator of the relationship between job strain and cardiometabolic disease.

methodsWe used data from five cohort studies from Australia, Finland, Sweden and UK, including 47 757 men and women. Data on job strain across two measurements 1-5 years apart (time 1 (T1)-time 2 (T2)) were used to define increase or decrease in job strain. Poor mental health (symptoms in the top 25% of the distribution of the scales) at T2 was considered a potential mediator in relation to incident cardiometabolic disease, including cardiovascular disease and diabetes, following T2 for a mean of 5-18 years.

resultsAn increase in job strain was associated with poor mental health (HR 1.56, 95% CI 1.38 to 1.76), and a decrease in job strain was associated with lower risk in women (HR 0.70, 95% CI 0.60-0.84). However, no clear association was observed between poor mental health and incident cardiometabolic disease (HR 1.08, 95% CI 0.96-1.23), nor between increase (HR 1.01, 95% CI 0.90-1.14) and decrease (HR 1.08, 95% CI 0.96-1.22) in job strain and cardiometabolic disease.

conclusionsThe results did not support that change in job strain is a risk factor for cardiometabolic disease and yielded no support for poor mental health as a mediator.

Indexed as

AdultAustraliaCardiovascular DiseasesCohort StudiesDiabetes MellitusEuropeFemaleHumansIncidenceMaleMental DisordersMiddle AgedOccupational StressProspective StudiesRisk FactorsSurveys and Questionnairescardiovasculardiabetes mellitusmental healthmeta-analysisstress

Identifiers

PMID31488605
PMCPMC6839729
OpenAlexW2971551520

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.