Evidence map›Paper›PMID 31488561›Full record

ArticleHaematologica2020

Defining signatures of peripheral T-cell lymphoma with a targeted 20-marker gene expression profiling assay.

Fanny Drieux, Philippe Ruminy, Ahmad Abdel-Sater, François Lemonnier, Pierre-Julien Viailly, Virginie Fataccioli, Vinciane Marchand, Bettina Bisig, Audrey Letourneau, Marie Parrens and 16 more

Open access · goldAbstract read
In one paragraph

Article in Haematologica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 36 citations in OpenAlex.

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  9. Haematologica · 2023
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  11. Disequilibrium betweenCancers · 2023
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

26 authors at 5 institutions in 2 countries.

Fanny DrieuxINSERM U1245, Centre Henri Becquerel, Rouen, France.
Philippe RuminyINSERM U1245, Centre Henri Becquerel, Rouen, France philippe.ruminy@chb.unicancer.fr.
Ahmad Abdel-SaterINSERM U1245, Centre Henri Becquerel, Rouen, France.
François LemonnierINSERM U955 and Université Paris-Est, Créteil, France.
Pierre-Julien ViaillyINSERM U1245, Centre Henri Becquerel, Rouen, France.
Virginie FataccioliINSERM U955 and Université Paris-Est, Créteil, France.
Vinciane MarchandINSERM U1245, Centre Henri Becquerel, Rouen, France.
Bettina BisigInstitut de Pathologie, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland.
Audrey LetourneauInstitut de Pathologie, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland.
Marie ParrensService d'Anatomie et Cytologie Pathologiques, Hôpital Haut-Lévêque, CHU de Bordeaux, France.
Céline BossardService d'Anatomie et Cytologie Pathologiques, CHU de Nantes, France.
Julie BruneauService d'Anatomie et Cytologie Pathologiques, Hôpital Universitaire Necker - Enfants Malades, Assistance Publique - Hôpitaux de Paris (APHP), Paris, France.
Pamela DobayInstitut de Pathologie, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland.
Liana VeresezanINSERM U1245, Centre Henri Becquerel, Rouen, France.
Aurélie DupuyINSERM U955 and Université Paris-Est, Créteil, France.
Anaïs PujalsINSERM U955 and Université Paris-Est, Créteil, France.
Cyrielle RobeINSERM U955 and Université Paris-Est, Créteil, France.
Nouhoum SakoINSERM U955 and Université Paris-Est, Créteil, France.
Christiane Copie-BergmanINSERM U955 and Université Paris-Est, Créteil, France.
Marie-Hélène Delfau-LarueINSERM U955 and Université Paris-Est, Créteil, France.
Jean-Michel PicquenotINSERM U1245, Centre Henri Becquerel, Rouen, France.
Hervé TillyINSERM U1245, Centre Henri Becquerel, Rouen, France.
Richard DelarueService Hématologie Adultes, Hôpital Universitaire Necker - Enfants Malades, Assistance Publique - Hôpitaux de Paris (APHP), Paris, France.
Fabrice JardinINSERM U1245, Centre Henri Becquerel, Rouen, France.
Laurence de LevalInstitut de Pathologie, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland.
Philippe GaulardINSERM U955 and Université Paris-Est, Créteil, France philippe.gaulard@aphp.fr.
Inserm · FRUniversity Hospital of Lausanne · CHHôpital Necker-Enfants Malades · FRCentre Hospitalier Universitaire de Bordeaux · FRCentre Hospitalier Universitaire de Nantes · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peripheral T-cell lymphoma comprises a heterogeneous group of mature non-Hodgkin lymphomas. Their diagnosis is challenging, with up to 30% of cases remaining unclassifiable and referred to as "not otherwise specified". We developed a reverse transcriptase-multiplex ligation-dependent probe amplification gene expression profiling assay to differentiate the main T-cell lymphoma entities and to study the heterogeneity of the "not specified" category. The test evaluates the expression of 20 genes, including 17 markers relevant to T-cell immunology and lymphoma biopathology, one Epstein-Barr virus-related transcript, and variants of

Indexed as

Epstein-Barr Virus InfectionsLymphoma, T-Cell, PeripheralAdultGene Expression ProfilingHerpesvirus 4, HumanHumansReproducibility of Results

Identifiers

PMID31488561
PMCPMC7271600
OpenAlexW2971971951

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.