Evidence map›Paper›PMID 31488490›Full record

ArticleBMJ open2019

Prevalence and correlates of cardiometabolic multimorbidity among hypertensive individuals: a cross-sectional study in rural South Asia-Bangladesh, Pakistan and Sri Lanka.

Liang Feng, Imtiaz Jehan, H Asita de Silva, Aliya Naheed, Hamida Farazdaq, Samina Hirani, Anuradhani Kasturiratne, Channa D Ranasinha, Md Tauhidul Islam, Ali Tanweer Siddiquee and 1 more

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 4 countries.

Liang FengProgram in Health Services & Systems Research, Duke-NUS Medical School, Singapore, Singapore.
Imtiaz Jehan *Department of Community Health Science, Aga Khan University, Karachi, Pakistan.
H Asita de Silva *Department of Pharmacology, University of Kelaniya Faculty of Medicine, Kelaniya, Sri Lanka.
Aliya Naheed *Initiative for Non-communicable Diseases, Health Systems and Population Studies Division, ICDDRB, Dhaka, Bangladesh.
Hamida FarazdaqDepartment of Family Medicine, Aga Khan University, Karachi, Pakistan.
Samina HiraniDepartment of Community Health Science, Aga Khan University, Karachi, Pakistan.
Anuradhani KasturiratneDepartment of Public Health, University of Kelaniya Faculty of Medicine, Ragama, Sri Lanka.
Channa D RanasinhaDepartment of Pharmacology, University of Kelaniya Faculty of Medicine, Kelaniya, Sri Lanka.
Md Tauhidul IslamInitiative for Non-communicable Diseases, Health Systems and Population Studies Division, ICDDRB, Dhaka, Bangladesh.
Ali Tanweer SiddiqueeInitiative for Non-communicable Diseases, Health Systems and Population Studies Division, ICDDRB, Dhaka, Bangladesh.
Tazeen H JafarProgram in Health Services & Systems Research, Duke-NUS Medical School, Singapore, Singapore tazeen.jafar@duke-nus.edu.sg.ORCID 0000-0001-7454-8376
Aga Khan University · PKInternational Centre for Diarrhoeal Disease Research · BDUniversity of Kelaniya · LKDuke-NUS Medical School · SG

Funding

Medical Research Council MR/N006178/1Wellcome Trust
6 · The paper itself

Abstract

objectiveTo determinate the prevalence and correlates of cardiometabolic multimorbidity (CMM), and their cross-country variation among individuals with hypertension residing in rural communities in South Asia.

designA cross-sectional study.

settingRural communities in Bangladesh, Pakistan and Sri Lanka.

participantsA total of 2288 individuals with hypertension aged ≥40 years from the ongoing Control of Blood Pressure and Risk Attenuation- Bangladesh, Pakistan and Sri Lanka clinical trial.

main outcome measuresCMM was defined as the presence of ≥2 of the conditions: diabetes, chronic kidney disease, heart disease and stroke. Logistic regression was done to evaluate the correlates of CMM.

resultsAbout 25.4% (95% CI 23.6% to 27.2%) of the hypertensive individuals had CMM. Factors positively associated with CMM included residing in Bangladesh (OR 3.42, 95% CI 2.52 to 4.65) or Sri Lankan (3.73, 95% CI 2.48 to 5.61) versus in Pakistan, advancing age (2.33, 95% CI 1.59 to 3.40 for 70 years and over vs 40-49 years), higher waist circumference (2.15, 95% CI 1.42 to 3.25) for Q2-Q3 and 2.14, 95% CI 1.50 to 3.06 for Q3 and above), statin use (2.43, 95% CI 1.84 to 3.22), and higher levels of triglyceride (1.01, 95% CI 1.01 to 1.02 per 5 mg/dL increase). A lower odds of CMM was associated with being physically active (0.75, 95% CI 0.57 to 0.97). A weak inverted J-shaped association between International Wealth Index and CMM was found (p for non-linear=0.058), suggesting higher risk in the middle than higher or lower socioeconomic strata.

conclusionsCMM is highly prevalent in rural South Asians affecting one in four individuals with hypertension. There is an urgent need for strategies to concomitantly manage hypertension, cardiometabolic comorbid conditions and associated determinants in South Asia.

Indexed as

AdultAgedBangladeshCross-Sectional StudiesDiabetes MellitusFemaleHeart DiseasesHumansHypertensionMaleMiddle AgedMultimorbidityPakistanPrevalenceProtective FactorsRenal Insufficiency, Chroniccardiometabolic multimorbidityhypertensionobesitySouth Asia

Identifiers

PMID31488490
PMCPMC6731877
OpenAlexW2971968817

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.