Evidence map›Paper›PMID 31488466›Full record

ArticleBMJ open2019

Medicines shortages in Pakistan: a qualitative study to explore current situation, reasons and possible solutions to overcome the barriers.

Muhammad Atif, Iram Malik, Irem Mushtaq, Saima Asghar

Abstract read
In one paragraph

Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed.

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  9. Review
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  13. Drug shortages in China: a cross-sectional study.BMC health services research · 2023
    Article
  14. Anesthetic drug shortages in Pakistan: a multicentre nationwide survey.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Experience of Pharmacists with Anti-Cancer Medicine Shortages in Pakistan: Results of a Qualitative Study.International journal of environmental research and public health · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Muhammad AtifDepartment of Pharmacy, Islamia University of Bahawalpur, Bahawalpur, Pakistan pharmacist_atif@yahoo.com.ORCID 0000-0001-6866-8152
Iram MalikDepartment of Pharmacy, Islamia University of Bahawalpur, Bahawalpur, Pakistan.ORCID 0000-0001-8029-7163
Irem MushtaqDepartment of Education, Islamia University of Bahawalpur, Bahawalpur, Pakistan.
Saima AsgharDepartment of Pharmacy, Islamia University of Bahawalpur, Bahawalpur, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study was conducted to assess current situation of medicines shortages in Pakistan and to identify its impact, reasons and possible solutions to overcome the barriers.

designA qualitative study.

settingThe study was conducted between May 2018 and July 2018 in three cities of Pakistan including Islamabad, Karachi and Bahawalpur, depending on the availability of most relevant key informants.

participantsHealth regulators, pharmaceutical manufacturers, pharmaceutical distributors and pharmacists. PRIMARY AND SECONDARY OUTCOME MEASURE: Study primarily explored current situation, reasons and potential solutions of medicines shortages in Pakistan. Secondary outcome was the issue of particular brand shortage.

methodSemistructured interviews were conducted. Sample size was determined by using saturation point criteria. Convenient sampling techniques were used to recruit the participants. The interviews were audiorecorded and transcribed verbatim. Data were analysed using inductive thematic analysis.

resultsA total of 41 stakeholders including 12 health regulators, 6 pharmaceutical manufacturers, 8 pharmaceutical distributors and 15 pharmacists participated in this study. Data analysis yielded 4 themes, 16 subthemes, 51 categories. Essential and life-saving medicines were in short supply. The major reasons of short supply of medicines were active pharmaceutical ingredient and raw material availability issues, lack of traditional distribution system and sudden demand fluctuation. Among proposed solutions, three most common were the facilitation and regulation of manufacturers, reasonable price fixation and improvements in the inventory control system.

conclusionMedicines were short in supply, and this may have clinical and financial impact on the patients in Pakistan. There were multiple and complex reasons of medicines shortages. Mandatory government leadership is required to resolve the issue on priority basis for improving the access of medicines to the patients.

Indexed as

Drug IndustryGovernment RegulationPharmaceutical PreparationsHealth Services Needs and DemandHumansPakistanQualitative ResearchQuality ControlPharmaceutical Preparationsbrand medicinesdrug regulatory authority of Pakistandrug shortagepricingshort medicines

Identifiers

PMID31488466
PMCPMC6731845

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.