ArticleJournal of orthopaedic surgery and research2019
Patients with Modic type 2 change have a severe radiographic representation in the process of lumbar degeneration: a retrospective imaging study.
Article in Journal of orthopaedic surgery and research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Incidence and risk factors for modic changes in the lumbar spine: a systematic review and meta-analysis.Frontiers in endocrinology · 2025Pooled it
- Strategic Use of the 30-Degree Endoscope in Biportal Endoscopic Lumbar Interbody Fusion for Spondylolisthesis With Severe Disc Height Loss: A Technique Note and Case Series.International journal of spine surgery · 2026Article
- Prevalence of modic changes in patients with low back pain and association with degenerative spinal findings: a retrospective MRI study.BMC musculoskeletal disorders · 2025Article
- New-Occurrence of Postoperative Modic Changes and Its Influence on the Surgical Prognosis After Percutaneous Endoscopic Lumbar Disc Discectomy.Orthopaedic surgery · 2025Article
- Correlation analysis of spine-pelvis parameters and age with lumbar paravertebral muscle degeneration in middle age and older adults.American journal of translational research · 2025Article
- Study and analysis of the correlation between lumbar spondylolisthesis and Modic changes.Frontiers in surgery · 2024Article
- Do Modic changes contribute to lumbar instability or other way around? A retrospective study based on their types, extents, and affected lumbar segments.BMC musculoskeletal disorders · 2023Article
- Article
- Risk Factors Involved in the Early and Medium-Term Poor Outcomes of Percutaneous Endoscopic Transforaminal Discectomy: A Single-Center Experience.Journal of pain research · 2022Article
- Correlation of Modic Changes with Sagittal Lumbopelvic Parameters.Journal of pain research · 2021Article
- Comparison of Percutaneous Transforaminal Endoscopic Decompression and Transforaminal Lumbar Interbody Fusion in the Treatment of Single-Level Lumbar Disc Herniation with Modic Type I Changes.Journal of pain research · 2021Article
- The Immune Privilege of the Intervertebral Disc: Implications for Intervertebral Disc Degeneration Treatment.International journal of medical sciences · 2020Review
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7 authors.
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Abstract
backgroundThere are few studies to investigate changes in imaging parameters of Modic changes (MCs). The imaging studies examining the distinctions in the lumbar sagittal parameters between MCs and lumbar disc degeneration (LDD) are still lacking. The purpose of this study was to identify the differences in the lumbar sagittal parameters among patients for LDD with/without Modic type 2 change (MII).
methodsA total of 208 patients with lumbar degenerative disease from January 2017 to August 2018 volunteered for this study. Sixty-two patients with MII were used as the MC group. The other 146 patients served as the disc degeneration (DD) group. The DD scores and sagittal parameters were measured on magnetic resonance imaging (MRI) and X-ray by using Surgimap software.
resultsThe prevalence of MII for patients with degenerative lumbar diseases in this study was 29.81%, primarily located at L5/S1. There were significant differences in lumbar lordosis (LL) and sacral slope (SS) between these two groups (P < 0.05). Similarly, the significant decrease in intervertebral height index (IHI) was found at L3-S1 in the MC group, compared with the DD group (P < 0.05). However, a significant difference in intervertebral angle (IVA) was observed only at L5/S1 (P < 0.05). The MC group had the smaller endplate concave angle (ECA) than the DD group from L3 caudal endplate to S1 cranial endplate (P < 0.05).
conclusionsMII has a severe radiographic representation in the process of lumbar degeneration than patients without MII, and the overconcentration of load caused by the smaller LL, SS, and IVA may be a reasonable explanation to answer why MCs are more common at the L5/S1.
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