ArticleBMC musculoskeletal disorders2019
Correlation between multifidus fatty atrophy and lumbar disc degeneration in low back pain.
Article in BMC musculoskeletal disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
89 citing papers in PubMed, 3 syntheses or guidelines pooled it, 144 citations in OpenAlex.
- Structural changes of the multifidus in animal models of intervertebral disk degeneration: a systematic review.Frontiers in surgery · 2024Pooled it
- The association between changes in multifidus muscle morphology and back pain scores following discectomy surgery for lumbar disc herniation: a systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2022Pooled it
- Imaging Evaluation of Fat Infiltration in Paraspinal Muscles on MRI: A Systematic Review with a Focus on Methodology.Orthopaedic surgery · 2021Pooled it
- The cervico-ocular reflex changes following treatment in individuals with subclinical neck pain: a randomized control trial.Experimental brain research · 2024Trial
- A randomized controlled trial comparing different sites of high-velocity low amplitude thrust on sensorimotor integration parameters.Scientific reports · 2024Trial
- Artificial Intelligence in Spine Neuroimaging: Diagnostic and Prognostic Utility of Novel Biomarkers in Lower Back Pain.Journal of clinical medicine · 2026Review
- Association Between Degeneration of the Paraspinal Muscles and Nerve Root Compression in Lumbar Disc Herniation Patients Who Underwent Percutaneous Endoscopic Lumbar Discectomy.Orthopaedic surgery · 2026Article
- Deduction of Back Pain Patients Using EMG Technology and Inertial Sensors During Functional Tests.Sensors (Basel, Switzerland) · 2026Article
- Preventing adjacent segment disease after lumbar fusion: a new perspective emphasizing individualized factors.Quantitative imaging in medicine and surgery · 2026Article
- Paraspinal Muscle Fatty Infiltration as a Predictor of Intervertebral Disc Degeneration and Pain Severity in Chronic Low Back Pain.Pain research & management · 2026Article
- Development of a prediction model for recurrent vertebral fractures in patients two years after vertebral augmentation using noninvasive data: a retrospective study.BMC musculoskeletal disorders · 2025Article
- Association between lumbar disc degeneration at L4-L5 level and atrophy of paraspinal muscles and gluteus medius: a cross-sectional study using 3T quantitative magnetic resonance imaging.BMC medical imaging · 2025Article
- Based on the mechanism of degeneration of the small joint - muscle - intervertebral disc complex and early intervention.Annals of medicine and surgery (2012) · 2025Article
- MRI grading of lumbar disc herniation based on AFFM-YOLOv8 system.Scientific reports · 2025Article
- Paraspinal muscles and gluteus medius fat infiltration are both associated with lumbar disc herniation.Insights into imaging · 2025Article
- Morphological characteristics of the thoracolumbar fascia: relationship to chronic low back pain and back extension strength.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Qualitative and quantitative characteristics of the lumbar multifidi muscles: Comparison of the magnetic resonance imaging and musculoskeletal ultrasound.Interventional pain medicine · 2025Article
- An Algorithmic Overview of Advanced Pain Therapies: A Narrative Review.Current pain and headache reports · 2025Review
- A Primer on Anatomy, Biophysics, Pathology, Imaging and Treatment of the Intervertebral Disc and the Anterior Spinal Column: The Discogenic, Intervertebral, Spinal Column (DISC) ASPN Workgroup.Journal of pain research · 2025Article
- Restorative Neurostimulation for Patients with Mechanical Chronic Low Back Pain and Impaired Neuromuscular Control of the Lumbar Spine | A New Treatment Paradigm.Journal of pain research · 2025Review
29 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChronic low back pain (LBP) is common and associated with lumbar disc herniation. The purpose of this study was to investigate if the grade of lumbar disc degeneration correlates with the degree of lumbar multifidus muscle (LMM) fatty atrophy.
methodsA retrospective analysis on 16 males and 19 females with chronic LBP and a mean age of 47.2 years. Using MRI, the grade of lumbar intervertebral discs degeneration was assessed according to the Pfirrmann classification at L4/L5 and L5/S1 levels. Fatty infiltration of the LMM was graded as normal, mild, moderate and severe. Adobe Photoshop CS6 was used for qualitative image analysis by measuring the Cross-sectional area (CSA) of the pure fat component of LMM.
resultsThere was a low correlation (R = 0.37) and significant association (ANOVA, p = 0.001, 95% CI 2.07-8.14) between the grade of lumbar disc degeneration and the degree of LMM fatty atrophy. Mean value of intervertebral disc degeneration was 2.9 for the L4/L5 level and 3.2 for L5/S1 respectively. The percentage of fat infiltration of the LMM at both studied levels showed a mean value of 22.91+/- 13.19% for L4/L5 and a higher mean value of 26.37+/- 12.89% for L5/S1. There were higher fatty atrophy scores in women and more disc degeneration in men.
conclusionThe percentage of LMM atrophy is higher in the lower levels (L5/S1) and shows a low correlation with the grade of disc degeneration.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.