ArticleBMC infectious diseases2019
Molecular characterization of human isolates of Strongyloides stercoralis and Rhabditis spp. based on mitochondrial cytochrome c oxidase subunit 1 (cox1).
Article in BMC infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Taxonomy ofParasitology · 2026Review
- Prevalence of strongyloidiasis in immunocompromised patients in Mazandaran province of northern Iran: A comprehensive study utilizing simultaneous parasitological, serological, and molecular techniques.Parasite epidemiology and control · 2025Article
- Synthesis and anthelmintic activity of novel thiosemicarbazide and 1,2,4-triazole derivatives: In vitro, in vivo, and in silico study.Journal of advanced research · 2024Article
- Anthelminthic and antimicrobial effects of hedge woundwort (Frontiers in pharmacology · 2024Article
- From past to present: opportunities and trends in the molecular detection and diagnosis of Strongyloides stercoralis.Parasites & vectors · 2023Review
- The first human case of rhabditiasis in Bangladesh.IDCases · 2023Article
- Evaluation of Anthelmintic and Anti-Inflammatory Activity of 1,2,4-Triazole Derivatives.Molecules (Basel, Switzerland) · 2022Article
- Discovery of Cinnamylidene Derivative of Rhodanine with High Anthelmintic Activity againstMolecules (Basel, Switzerland) · 2022Article
- Molecular typing ofParasitology · 2022Observational
- An annotated checklist of the eukaryotic parasites of humans, exclusive of fungi and algae.ZooKeys · 2021Article
- Seroprevalence ofIranian journal of parasitologyArticle
- Genetic Diversity ofIranian journal of parasitologyArticle
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Authors and funding
5 authors.
Funding
Abstract
backgroundDue to the similarity of Strongyloides stercoralis with free-living nematodes of Rhabditis species they might be miss-diagnosed with each other in microscopical examination of stool samples. The aim of this study was molecular characterization and differentiation of human derived isolates of S. stercoralis and Rhabditis species based on the mitochondrial gene of cytochrome c oxidase subunit 1 (cox1) amplification.
methodsUsing parasitological methods, ten isolates of S. stercoralis and three isolates of Rhabditis spp. were obtained from fresh stool samples of patients and the genomic DNA of the samples were extracted. PCR amplification of cox1 gene was carried out for all the isolates and the products were sequenced.
resultsThe phylogenetic analysis illustrated that S. stercoralis and Rhabditis spp. isolates were placed in two distinguishable separate clades. Inter-species genetic variation between isolates of S. stercoralis and Rhabditis spp. were ranged from 13.5 to 14.5%.
conclusionsCox1 gene was a suitable marker for discrimination of S. stercoralis from Rhabditis spp. retrieved from human in the current study. The availability of gene sequence information will be helpful in the future development and validation of discriminatory PCR-based assays of these nematodes.
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