Evidence map›Paper›PMID 31488064›Full record

Trial reportBMC infectious diseases2019

DOES IT WORK? -a randomized controlled trial to test the efficacy of HCV and HIV-related education on drug users in MMT, China.

Jing Ying Zhang, Zhi Bin Li, Lei Zhang, Jun Wang, Le Ping Huang, Gui Lai Zhan, Zhu Li, Jiang Du, Min Zhao

Registry-linked trialOpen access · goldAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01647191 (Reducing Hepatitis C Virus), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01647191 nacompletednot on this map

Reducing Hepatitis C Virus (HCV)/Human Immunodeficient Virus (HIV) Risk Behaviors Among Injection Drug Users in China

TypeinterventionalSponsorShanghai Mental Health CenterRan2011 to 2015Enrolled240ConditionsHepatitis CArmsintervention group, control group
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Education of Adolescents in the Prevention of HIV/AIDS in the Czech Republic.International journal of environmental research and public health · 2021
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Jing Ying ZhangCollaborative Innovation Center for Brain Science, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, 600 South Wanping Road, Shanghai, 200030, China.
Zhi Bin LiMental Health Center of Jiading District in Shanghai, Shanghai, China.
Lei ZhangCollaborative Innovation Center for Brain Science, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, 600 South Wanping Road, Shanghai, 200030, China.
Jun WangMental Health Center of Yangpu District in Shanghai, Shanghai, China.
Le Ping HuangMental Health Center of Hongkou District in Shanghai, Shanghai, China.
Gui Lai ZhanMental Health Center of Xuhui District in Shanghai, Shanghai, China.
Zhu LiSongnan Community Health Service Center, Baoshan District, Shanghai, China.
Jiang DuCollaborative Innovation Center for Brain Science, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, 600 South Wanping Road, Shanghai, 200030, China. dujiangdou@163.com.ORCID http://orcid.org/0000-0003-4014-1070
Min ZhaoCollaborative Innovation Center for Brain Science, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, 600 South Wanping Road, Shanghai, 200030, China. drminzhao@gmail.com.
Shanghai Mental Health Center · CNShanghai Jiao Tong University · CNJiading District Central Hospital · CN

Funding

Key Subject Construction of Jiading District Mental Health JDYXZDZK-3key subject of Shanghai Municipal Health and Family Planning Commission(Psychiatry) 2017ZZ02021National Key R&D Program of China 2017YFC1310400National Natural Science Foundation of China 81771436National Natural Science Foundation of China U1502228Program of Shanghai Academic Research Leader 17XD1403300Shanghai Key Laboratory of Psychotic Disorders 13DZ2260500Shanghai Municipal Education Commission-Gaofeng Clinical Medicine Grant Support 20152235Shanghai Municipal Health and Family Planning Commission joint research project 2014ZYJB0002
6 · The paper itself

Abstract

backgroundHCV (Hepatitis C virus) is a prevalent chronic disease with potentially deadly consequences, especially for drug users. However, there are no special HCV or HIV (human immunodeficiency virus)-related intervention programs that are tailored for drug users in China; to fill this gap, the purpose of this study was to explore HCV and HIV-related knowledge among drug users in MMT (methadone maintenance treatment) sites of China and to investigate the effectiveness of HCV and HIV-related education for improving the knowledge of IDUs (injection drug users) and their awareness of infection.

methodsThe study was a randomized cluster controlled trial that compared a usual care group to a usual care plus HCV/HIV-REP (HCV/HIV-Reduction Education Program) group with a 24-week follow-up. The self-designed questionnaires, the HCV- and HIV-related knowledge questionnaire and the HIV/HCV infection awareness questionnaire, were used to collect the data. Four MMT clinics were selected for this project; two MMT clinics were randomly assigned to the research group, with subjects receiving their usual care plus HCV/HIV-REP, and the remaining two MMT clinics were the control group, with subjects receiving their usual care over 12 weeks. Sixty patients were recruited from each MMT clinic. A total of 240 patients were recruited. Follow-up studies were conducted at the end of the 12th week and the 24th week after the intervention.

resultsAt baseline, the mean score (out of 20 possible correct answers) for HCV knowledge among the patients in the group receiving the intervention was 6.51 (SD = 3.5), and it was 20.57 (SD = 6.54) for HIV knowledge (out of 45 correct answers) and 8.35 (SD = 2.8) for HIV/HCV infection awareness (out of 20 correct answers). At the 12-week and 24-week follow-up assessments, the research group showed a greater increase in HCV-/HIV-related knowledge (group × time effect, F = 37.444/11.281, P < 0.05) but no difference in their HIV/HCV infection awareness (group × time effect, F = 2.056, P > 0.05).

conclusionAn MMT-based HCV/HIV intervention program could be used to improve patient knowledge of HCV and HIV prevention, but more effort should be devoted to HIV/HCV infection awareness.

trial registrationProtocols for this study were approved by institution review board (IRB) of Shanghai Mental Health Center (IRB:2009036), and registered in U.S national institutes of health (http://www.clinicaltrials.gov, NCT01647191 ). Registered 23 July 2012.

Indexed as

Opiate Substitution TreatmentPatient Education as TopicAdultAwarenessChinaCluster AnalysisDrug UsersEfficiency, OrganizationalFemaleHealth Knowledge, Attitudes, PracticeHepacivirusHepatitis CHIVHIV InfectionsHumansMaleMethadoneDrug usersHCVHIVInfection awarenessKnowledgeMMT

Identifiers

PMID31488064
PMCPMC6727322
OpenAlexW2971808058

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.