Evidence map›Paper›PMID 31488013›Full record

ArticleRenal failure2019

The inhibition of Nrf2 accelerates renal lipid deposition through suppressing the ACSL1 expression in obesity-related nephropathy.

Yinyin Chen, Liyu He, Yiya Yang, Ying Chen, Yanran Song, Xi Lu, Yumei Liang

Open access · goldAbstract read
In one paragraph

Article in Renal failure, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
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  3. NRF2 Dysregulation and Therapeutic Insights Across Chronic Kidney Diseases.International journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Yinyin ChenDepartment of Nephrology, Laboratory of Kidney Disease, Hunan Provincial People's Hospital, Hunan Normal University , Changsha , Hunan , P.R. China.
Liyu HeKey Lab of Kidney Disease and Blood Purification in Hunan, Department of Nephrology, The Second Xiangya Hospital Central South University , Changsha , Hunan , People's Republic of China.
Yiya YangDepartment of Nephrology, Laboratory of Kidney Disease, Hunan Provincial People's Hospital, Hunan Normal University , Changsha , Hunan , P.R. China.
Ying ChenDepartment of Nephrology, Laboratory of Kidney Disease, Hunan Provincial People's Hospital, Hunan Normal University , Changsha , Hunan , P.R. China.
Yanran SongDepartment of Nephrology, Laboratory of Kidney Disease, Hunan Provincial People's Hospital, Hunan Normal University , Changsha , Hunan , P.R. China.
Xi LuDepartment of Nephrology, Laboratory of Kidney Disease, Hunan Provincial People's Hospital, Hunan Normal University , Changsha , Hunan , P.R. China.
Yumei LiangDepartment of Nephrology, Laboratory of Kidney Disease, Hunan Provincial People's Hospital, Hunan Normal University , Changsha , Hunan , P.R. China.
Hunan Normal University · CNHunan Provincial People's Hospital · CNCentral South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAnimalsBiopsyCell LineCoenzyme A LigasesDisease Models, AnimalDown-RegulationFatty Acids, NonesterifiedFemaleGene Knockdown TechniquesHumansKidney DiseasesKidney TubulesMaleMiceMicroscopy, ElectronACSL1 protein, humanACSL1 protein, mouseCoenzyme A LigasesFatty Acids, NonesterifiedNFE2L2 protein, humanNfe2l2 protein, mouseNF-E2-Related Factor 2Reactive Oxygen SpeciesRNA, Small InterferingTriglyceridesACSL1lipid depositionNrf2obesity-related nephropathyOxidative stress

Identifiers

PMID31488013
PMCPMC6735294
OpenAlexW2971400725

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.