Evidence map›Paper›PMID 31487940›Full record

ReviewGenes2019

Molecular Strategies for RPGR Gene Therapy.

Jasmina Cehajic Kapetanovic, Michelle E McClements, Cristina Martinez-Fernandez de la Camara, Robert E MacLaren

Open access · goldAbstract readReview
In one paragraph

Review in Genes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Ciliary Defects in Inherited Retinal Diseases.Advanced genetics (Hoboken, N.J.) · 2026
    Review
  3. Review
  4. Review
  5. Robotising vitreoretinal surgeries.Eye (London, England) · 2025
    Review
  6. Article
  7. Cold Spring Harbor perspectives in medicine · 2023
    Review
  8. Article
  9. Retinitis Pigmentosa: Current Clinical Management and Emerging Therapies.International journal of molecular sciences · 2023
    Review
  10. Impaired glutamylation of RPGRProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  11. Review
  12. Article
  13. A novel mutation ofInternational journal of ophthalmology · 2022
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. International journal of molecular sciences · 2020
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jasmina Cehajic KapetanovicNuffield Laboratory of Ophthalmology, University of Oxford, Oxford OX3 9DU, UK. 'jasmina.kapetanovic@eye.ox.ac.uk.
Michelle E McClementsNuffield Laboratory of Ophthalmology, University of Oxford, Oxford OX3 9DU, UK.
Cristina Martinez-Fernandez de la CamaraNuffield Laboratory of Ophthalmology, University of Oxford, Oxford OX3 9DU, UK.
Robert E MacLarenNuffield Laboratory of Ophthalmology, University of Oxford, Oxford OX3 9DU, UK.
University of Oxford · GB

Funding

Department of HealthMedical Research Council G1000268
6 · The paper itself

Abstract

Mutations affecting the

Indexed as

AnimalsClinical Trials as TopicDependovirusEye ProteinsGene EditingGenetic TherapyHumansRetinitis PigmentosaEye ProteinsRPGR protein, humanadeno-associated viralgene therapyRetinitis Pigmentosa GTPase RegulatorRetinitis Pigmentosa (RP)

Identifiers

PMID31487940
PMCPMC6770968
OpenAlexW2972243172

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.