Evidence map›Paper›PMID 31487938›Full record

ArticleInternational journal of molecular sciences2019

Iron Release Profile of Silica-Modified Zero-Valent Iron NPs and Their Implication in Cancer Therapy.

Li-Xing Yang, Ya-Na Wu, Pei-Wen Wang, Wu-Chou Su, Dar-Bin Shieh

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Development of AuACS applied materials & interfaces · 2026
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  5. Review
  6. Nanoparticles in Dentistry: A Comprehensive Review.Pharmaceuticals (Basel, Switzerland) · 2021
    Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Li-Xing YangInstitute of Basic Medical Sciences, National Cheng Kung University, Tainan 70101, Taiwan.
Ya-Na WuInstitute of Oral Medicine and Department of Stomatology, College of Medicine, National Cheng Kung University Hospital, National Cheng Kung University, Tainan 70101, Taiwan.
Pei-Wen WangInstitute of Oral Medicine and Department of Stomatology, College of Medicine, National Cheng Kung University Hospital, National Cheng Kung University, Tainan 70101, Taiwan.
Wu-Chou SuDepartment of Internal Medicine, Division of Hematology/Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 70101, Taiwan. sunnysu@mail.ncku.edut.tw.
Dar-Bin ShiehInstitute of Basic Medical Sciences, National Cheng Kung University, Tainan 70101, Taiwan. darbinshieh@gmail.com.
National Cheng Kung University Hospital · TWInstitute of Biological Chemistry, Academia Sinica · TWNational Cheng Kung University · TW

Funding

Ministry of Science and Technology, Taiwan 104-2314-B-006-063-MY3Ministry of Science and Technology, Taiwan 106-2627-M-006-001Ministry of Science and Technology, Taiwan 107-2321-B-006-019
6 · The paper itself

Abstract

To evaluate the iron ion release profile of zero-valent iron (ZVI)-based nanoparticles (NPs) and their relationship with lysosomes in cancer cells, silica and mesoporous silica-coated ZVI NPs (denoted as ZVI@SiO

Indexed as

AnimalsApoptosisCell Line, TumorCells, CulturedDrug LiberationHumansIronLysosomesMaleMetal NanoparticlesMiceMice, Inbred NODMice, SCIDNeoplasms, ExperimentalReactive Oxygen SpeciesSilicon DioxideIronReactive Oxygen SpeciesSilicon Dioxideiron releaselysosomereactive oxygen speciessilicazero-valent iron

Identifiers

PMID31487938
PMCPMC6770483
OpenAlexW2971828342

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.