Evidence map›Paper›PMID 31487860›Full record

ArticleMolecules (Basel, Switzerland)2019

Félix Matadamas-Martínez, Alicia Hernández-Campos, Alfredo Téllez-Valencia, Alejandra Vázquez-Raygoza, Sandra Comparán-Alarcón, Lilián Yépez-Mulia, Rafael Castillo

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Review
  3. Molecular interaction assaysThe journal of venomous animals and toxins including tropical diseases · 2025
    Article
  4. Article
  5. Targeting Trypanothione Metabolism in Trypanosomatids.Molecules (Basel, Switzerland) · 2024
    Review
  6. Review
  7. In Silico Exploration of the Trypanothione Reductase (TryR) ofInternational journal of molecular sciences · 2023
    Article
  8. Article
  9. Review
  10. Article
  11. Metabolic Pathways ofPharmaceutics · 2022
    Review
  12. Article
  13. Benzimidazole Derivatives as New and Selective Inhibitors of Arginase fromInternational journal of molecular sciences · 2021
    Article
  14. New Phosphoramidates Containing Selenium as Leishmanicidal Agents.Antimicrobial agents and chemotherapy · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Félix Matadamas-MartínezDepartamento de Farmacia, Facultad de Química, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.
Alicia Hernández-CamposDepartamento de Farmacia, Facultad de Química, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.
Alfredo Téllez-ValenciaFacultad de Medicina y Nutrición, Universidad Juárez del Estado de Durango Av. Universidad y Fanny Anitúa S/N, Durango 34000, Mexico.
Alejandra Vázquez-RaygozaFacultad de Medicina y Nutrición, Universidad Juárez del Estado de Durango Av. Universidad y Fanny Anitúa S/N, Durango 34000, Mexico.
Sandra Comparán-AlarcónUnidad de Investigación Médica en Enfermedades Infecciosas y Parasitarias, Unidad Médica de Alta Especialidad-Hospital de Pediatría, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City 06720, Mexico.
Lilián Yépez-MuliaUnidad de Investigación Médica en Enfermedades Infecciosas y Parasitarias, Unidad Médica de Alta Especialidad-Hospital de Pediatría, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City 06720, Mexico. lilianyepez@yahoo.com.
Rafael CastilloDepartamento de Farmacia, Facultad de Química, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico. rafaelc@unam.mx.ORCID 0000-0001-8675-5671
Mexican Social Security Institute · MXUniversidad Juárez del Estado de Durango · MXUniversidad Nacional Autónoma de México · MX

Funding

Consejo Nacional de Ciencia y Tecnología 251726.Fondo de Investigación en Salud, Instituto Mexicano del Seguro Social FIS/IMSS/PROT/G16/1618
6 · The paper itself

Abstract

Leishmanicidal drugs have many side effects, and drug resistance to all of them has been documented. Therefore, the development of new drugs and the identification of novel therapeutic targets are urgently needed.

Indexed as

Amino Acid SequenceBinding SitesDose-Response Relationship, DrugEnzyme InhibitorsHydrogen BondingLeishmania mexicanaMolecular ConformationMolecular Docking SimulationMolecular Dynamics SimulationMolecular StructureNADH, NADPH OxidoreductasesPharmacokineticsRecombinant ProteinsStructure-Activity RelationshipTrypanocidal AgentsEnzyme InhibitorsNADH, NADPH OxidoreductasesRecombinant ProteinsTrypanocidal Agentstrypanothione reductaseenzyme inhibitorsleishmanicidal activitymolecular dockingtrypanothione reductase

Identifiers

PMID31487860
PMCPMC6767256
OpenAlexW2972203631

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.