Evidence map›Paper›PMID 31487854›Full record

ArticleNutrients2019

The Relationship of Obesity, Nutritional Status and Muscle Wasting in Patients Assessed for Liver Transplantation.

Helen Vidot, Katharine Kline, Robert Cheng, Liam Finegan, Amelia Lin, Elise Kempler, Simone I Strasser, David Geoffrey Bowen, Geoffrey William McCaughan, Sharon Carey and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. Screening and Diagnosis of Malnutrition in Individuals With Obesity: A Scoping Review of Current Methods.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
    Article
  3. Association of Hormonal Status With Sarcopenia, Frailty and Outcome in Patients With Decompensated Cirrhosis.Liver international : official journal of the International Association for the Study of the Liver · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. [Research progress of sarcopenic obesity and chronic liver disease].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2023
    Review
  8. Bariatric surgery in liver cirrhosis.Frontiers in surgery · 2022
    Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Helen VidotDepartment Nutrition & Dietetics, Royal Prince Alfred Hospital, Camperdown, 2050 NSW, Australia. helen.vidot@health.nsw.gov.au.ORCID 0000-0001-8084-9968
Katharine KlineSydney Medical School, The University of Sydney, Sydney, 2006 NSW, Australia.
Robert ChengLiver Injury and Cancer, Centenary Research Institute, The University of Sydney, Sydney, 2006 NSW, Australia.
Liam FineganSchool of Business, The University of Sydney, Sydney, 2006 NSW, Australia.
Amelia LinSydney Medical School, The University of Sydney, Sydney, 2006 NSW, Australia.
Elise KemplerSydney Medical School, The University of Sydney, Sydney, 2006 NSW, Australia.
Simone I StrasserSydney Medical School, The University of Sydney, Sydney, 2006 NSW, Australia.ORCID 0000-0001-6374-1525
David Geoffrey BowenLiver Injury and Cancer, Centenary Research Institute, The University of Sydney, Sydney, 2006 NSW, Australia.
Geoffrey William McCaughanLiver Injury and Cancer, Centenary Research Institute, The University of Sydney, Sydney, 2006 NSW, Australia.
Sharon CareyDepartment Nutrition & Dietetics, Royal Prince Alfred Hospital, Camperdown, 2050 NSW, Australia.
Margaret Allman-FarinelliSchool of Life and Environmental Sciences Charles Perkins Centre, The University of Sydney, Sydney, 2006 NSW, Australia.ORCID 0000-0002-6478-1374
Nicholas Adam ShackelLiver Injury and Cancer, Centenary Research Institute, The University of Sydney, Sydney, 2006 NSW, Australia.
The University of Sydney · AURoyal Prince Alfred Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionObesity co-exists with malnutrition and muscle atrophy in patients with cirrhosis. Muscle wasting is a feature of sarcopenia, a known determinant of patient outcomes. This is the first description of a relationship between obesity, subjective global assessment (SGA) of nutritional status and muscle wasting in patients with cirrhosis.

methodsThe relationship between body mass index (BMI with obesity defined as ≥ 30 kg/m

resultsThere were 205 patients, of whom 70% were males. The mean age was 52 ± 0.7 years and the Model for End-Stage Liver Disease (MELD) score was 16.8 ± 0.5. Overall, 31% of patients were obese and 56% of well-nourished (SGA A) individuals were obese. Muscle wasting was identified in 86% of all patients, irrespective of their nutritional status (A, B, C). All obese males classified as well-nourished (SGA A) were sarcopenic and 62% of obese females classified as SGA A were sarcopenic. Muscle wasting was worse in obese individuals (cTPA 230.9 mm

conclusionObesity combined with muscle wasting is common in patients with cirrhosis. Muscle wasting is common in well-nourished (SGA A) obese patients. Consequently, all patients assessed for liver transplantation should undergo additional screening for malnutrition and muscle wasting irrespective of BMI.

Indexed as

Liver TransplantationMuscular AtrophyNutritional StatusObesityCross-Sectional StudiesFemaleHumansLiver CirrhosisMaleMiddle AgedNutrition Assessmentcirrhosisliver transplantationmuscle wastingnutritional statusobesity

Identifiers

PMID31487854
PMCPMC6769900
OpenAlexW2972054718

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.