Evidence map›Paper›PMID 31487819›Full record

Trial reportNutrients2019

Native Whey Induces Similar Adaptation to Strength Training as Milk, despite Higher Levels of Leucine, in Elderly Individuals.

Håvard Hamarsland, Mathias K Johansen, Fridtjof Seeberg, Marie Brochmann, Ina Garthe, Haakon B Benestad, Truls Raastad

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Vitamin DJournal of cachexia, sarcopenia and muscle · 2021
    Trial
  5. Review
  6. Review
  7. Review
  8. Review
  9. Betaine, a component ofFood science & nutrition · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Håvard HamarslandDepartment of Physical Performance, Norwegian School of Sport Sciences, P.O. Box 4014 Ullevål Stadion, 0806 Oslo, Norway. havard.hamarsland@gmail.com.ORCID 0000-0002-7343-2774
Mathias K JohansenDepartment of Physical Performance, Norwegian School of Sport Sciences, P.O. Box 4014 Ullevål Stadion, 0806 Oslo, Norway.
Fridtjof SeebergDepartment of Physical Performance, Norwegian School of Sport Sciences, P.O. Box 4014 Ullevål Stadion, 0806 Oslo, Norway.
Marie BrochmannDepartment of Health, Nutrition and Management, Faculty of Health Sciences, Oslo and Akershus University College of Applied Sciences, 0130 Oslo, Norway.
Ina GartheNorwegian Olympic Federation, 0863 Oslo, Norway.
Haakon B BenestadSection of Anatomy, Institute of Basic Medical Sciences, University of Oslo, 0317 Oslo, Norway.ORCID 0000-0003-3398-618X
Truls RaastadDepartment of Physical Performance, Norwegian School of Sport Sciences, P.O. Box 4014 Ullevål Stadion, 0806 Oslo, Norway.ORCID 0000-0002-2567-3004
Norwegian School of Sport Sciences · NOOsloMet – Oslo Metropolitan University · NOUniversity of Oslo · NO

Funding

Norges Forskningsråd 225258
6 · The paper itself

Abstract

backgroundLarge amounts of protein (40 g) or supplementing suboptimal servings of protein with leucine are able to overcome the anabolic resistance in elderly muscle. Our aim was to compare the effects of supplementation of native whey, high in leucine, with milk on gains in muscle mass and strength during a period of strength training, in elderly individuals.

methodsIn this double-blinded, randomized, controlled study, a total of 30 healthy men and women received two daily servings of 20 g of either milk protein or native whey, during an 11-week strength training intervention. Muscle strength, lean mass, m. vastus lateralis thickness, muscle fiber area, and resting and post-exercise phosphorylation of p70S6K, 4E-BP1, and eEF-2 were assessed prior to and after the intervention period.

resultsMuscle mass and strength increased, by all measures applied in both groups (

conclusionSupplementation with milk or native whey during an 11-week strength training period increased muscle mass and strength similarly in healthy elderly individuals.

Indexed as

Resistance TrainingAdaptation, PhysiologicalAgedAgingAnimalsBiopsyDietDouble-Blind MethodFemaleHumansLeucineMaleMilkMuscle, SkeletalWhey ProteinsLeucineWhey Proteinsamino acidsgerontologymTORC-1protein qualityprotein supplementationresistance exercise

Identifiers

PMID31487819
PMCPMC6770720
OpenAlexW2971478361

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.