ArticleEuropean journal of dentistry2019
Potential of Distilled Liquid Smoke Derived from Coconut (Cocos nucifera L) Shell for Traumatic Ulcer Healing in Diabetic Rats.
Article in European journal of dentistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
23 citing papers in PubMed, 56 citations in OpenAlex.
- Blood Vessel, VEGF, and FGF Expression in Traumatic Ulcer Healing of Wister Rats after Application of Chitosan-Aloe vera Gel.European journal of dentistry · 2026Article
- Establishment of an oral burn model in streptozotocin-induced diabetic rats.Maxillofacial plastic and reconstructive surgery · 2024Article
- In Silico Study of Liquid Smoke Rice Husk against COVID-19.European journal of dentistry · 2023Article
- Osteoblast Viability of Liquid Smoke Rice Hull and Nanoparticles Form as Periodontitis Treatment.European journal of dentistry · 2023Article
- Exploration of the Interrelationship within Biomass Pyrolysis Liquid Composition Based on Multivariate Analysis.Molecules (Basel, Switzerland) · 2022Article
- The Cytokine and Bone Protein Expression by Ellagic Acid-Hydroxyapatite in Bone Remodelling Model.TheScientificWorldJournal · 2022Article
- The Role of Recombinant Secretory Leukocyte Protease Inhibitor to CD163, FGF-2, IL-1 and IL-6 Expression in Skin Wound Healing.Clinical, cosmetic and investigational dermatology · 2022Article
- The Effect of Lipoteichoic Acid from Lactobacillus plantarum on Dental Pulp Inflammation.European journal of dentistry · 2021Article
- The Effects of Rice Husk Liquid Smoke in Porphyromonas gingivalis-Induced Periodontitis.European journal of dentistry · 2021Article
- Growth factor stimulation for the healing of traumatic ulcers with liquid rice hull smoke.Journal of Taibah University Medical Sciences · 2021Article
- The differences in the number of fibroblasts and blood vessels after the topical and systemic administration ofVeterinary world · 2021Article
- The NF-kB and Collagen Type 1 Expression in Dental Pulp after Treated Calcium Hydroxide Combined with Propolis.European journal of dentistry · 2021Article
- Role of Hydroxyapatite and Ellagic Acid in the Osteogenesis.European journal of dentistry · 2021Article
- The Role of Rice Hull Liquid Smoke in the Traumatic Ulcer Healing.European journal of dentistry · 2021Article
- Role of Inflammatory Cell Responses in Stimulating Fibroblasts in Diabetic Oral Ulcer after Treatment with Liquid Smoke of Coconut Endocarp: A Histological Assessment.European journal of dentistry · 2021Article
- The Macrophage Responses during Diabetic Oral Ulcer Healing by Liquid Coconut Shell Smoke: An Immunohistochemical Analysis.European journal of dentistry · 2020Article
- Anti-Inflammatory Effect of Musa acuminata Stem.European journal of dentistry · 2020Article
- Bovine sponge amnion stimulates socket healing: A histological analysis.Journal of advanced pharmaceutical technology & researchArticle
- The effect of secretory leukocyte protease inhibitor amnion membrane on incisional wound healing.Journal of oral biology and craniofacial researchArticle
- Cytotoxicity and proliferation evaluation on fibroblast after combining calcium hydroxide and ellagic acid.Journal of advanced pharmaceutical technology & researchArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveDistilled liquid smoke (DLS) is a result of coconut processing by-product that not only serves as a natural food preservative but also has a promising therapeutic effect. The healing potential of DLS derived from coconut ( MATERIALS AND
methodsDLS was analyzed the component by gas chromatograph mass spectrometry. Diabetic condition was induced by alloxan in 55 male Wistar rats. Ten mm of traumatic ulcer was made along the labial fornix incisive inferior after the diabetic condition was confirmed. Then DLS coconut shell, benzydamine hydrochloride, and sterile distilled water were applied topically for 3, 5, and 7 days. The potential healing was evaluated based on the expression of nuclear factor kappa beta (NFκB) and tumor necrosis factor alpha (TNF-α) on macrophages using immunohistochemical staining and the amount of collagen using Masson Trichome staining. The difference between each group was analyzed using one-way analysis of variance. The least significant difference test is used to determine the significant difference (
resultsThe major compounds found were phenol (36.6%), 2-methoxyphenol (guaiacol) (25.2%), furfural (17.8%), and 4-ethyl-2-methoxyphenol (3.5%) with 28 other minor constituents. The lowest NFκB and TNF-α expression on macrophage was observed by topical application of DLS derived from coconut shell for 3, 5, and 7 days of treatment. The amount of collagen was increased and indicated by the highest result of DLS compared to others.
conclusionThe DLS derived from coconut (
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.