Evidence map›Paper›PMID 31487545›Full record

ArticleJournal of the American College of Cardiology2019

Mobile Photoplethysmographic Technology to Detect Atrial Fibrillation.

Yutao Guo, Hao Wang, Hui Zhang, Tong Liu, Zhaoguang Liang, Yunlong Xia, Li Yan, Yunli Xing, Haili Shi, Shuyan Li and 6 more

3 registry-linked trialsOpen access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Journal of the American College of Cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 257 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
257citing papers in PubMed, 7 pooled it
24.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05442203 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Electrocardiogram-based Artificial Intelligence-assisted Detection of Heart Disease

TypeinterventionalSponsorTempus AIRan2022 to 2025Enrolled1,000ConditionsAtrial Fibrillation, Structural Heart DiseaseArmsZio Patch Monitor, Echocardiogram
NCT06671171 completednot on this mapstarted 2025, after this paper: background citation

Wearable Assessment of Thoracic, Cardiac Health and Exercise Performance Trial

TypeobservationalSponsorThe University of Hong KongRan2025 to 2026Enrolled50ConditionsCongenital Heart Disease, Pulmonary Hypertension, Heart Failure, Coronary Artery DiseaseArmsApple Watch Series 9
NCT07663799 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Wearable Assessment of Thoracic, Cardiac Health and Exercise Performance Trial Prospective (WATCH-XP)

TypeobservationalSponsorThe University of Hong KongRan2026 to 2028Enrolled20ConditionsCongenital Heart Disease, Pulmonary Hypertension, Heart Failure, Coronary Heart Disease (CHD)ArmsApple Watch Series 9
3 · Its place in the literature

Who cites it

257 citing papers in PubMed, 7 syntheses or guidelines pooled it, 470 citations in OpenAlex.

  1. Guideline
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  7. Telemonitoring of Real-World Health Data in Cardiology: A Systematic Review.International journal of environmental research and public health · 2021
    Pooled it
  8. Digital recruitment and prevalence of screen-detected atrial fibrillation in nationwide patch-based ECG screening: the NORSCREEN randomized clinical trial.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
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  17. Role of telemedicine in cardiovascular care in low- and middle-income countries (LMICs).American heart journal plus : cardiology research and practice · 2026
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197 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 12 institutions in 4 countries.

Yutao GuoChinese People's Liberation Army General Hospital, Beijing, China.
Hao WangChinese People's Liberation Army General Hospital, Beijing, China.
Hui ZhangChinese People's Liberation Army General Hospital, Beijing, China.
Tong LiuTianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease, Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University, Tianjin, China.
Zhaoguang LiangThe First Affiliated Hospital of Haerbing Medical University, Haerbing, China.
Yunlong XiaThe First Affiliated Hospital of Dalian Medical University, Dalian, China.
Li YanYunnan Cardiovascular Hospital, Kunmin, China.
Yunli XingBeijing Friendship Hospital, Capital Medical University, Beijing, China.
Haili ShiZhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, China.
Shuyan LiThe First Hospital of Jilin University, Changchun, Jilin, China.
Yanxia LiuGeneral Hospital of Shenyang Military, Shenyang, China.
Fan LiuThe Second Hospital of Hebei Medical University, Shijiazhuang, China.
Mei FengShanxi Da Hospital, Taiyuan, China.
Yundai ChenChinese People's Liberation Army General Hospital, Beijing, China. Electronic address: cyundai@vip.163.com.
Gregory Y H LipLiverpool Centre for Cardiovascular Sciences, University of Liverpool, Liverpool, United Kingdom; Aalborg Thrombosis Research Unit, Department of Clinical Medicine, Aalborg University, Aalborg, Denmark. Electronic address: gregory.lip@liverpool.ac.uk.
MAFA II Investigators
Chinese PLA General Hospital · CNHebei Medical University · CNChinese People's Liberation Army · CNCapital Medical University · CNZhengzhou Central Hospital · CNDalian Medical University · CNGeneral Hospital of Shenyang Military Region · CNJilin University · CNSecond Hospital of Tianjin Medical University · CNUniversity of Liverpool · GBFuwai Yunnan Cardiovascular Hospital · CNPeople's Liberation Army No. 150 Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLow detection and nonadherence are major problems in current management approaches for patients with suspected atrial fibrillation (AF). Mobile health devices may enable earlier AF detection and improved AF management.

objectivesThis study sought to investigate the effectiveness of AF screening in a large population-based cohort using smart device-based photoplethysmography (PPG) technology, combined with a clinical care AF management pathway using a mobile health approach.

methodsAF screening was performed with smart devices using PPG technology, which were made available for the population ≥18 years of age across China. Monitoring for at least 14 days with a wristband (Honor Band 4) or wristwatch (Huawei Watch GT, Honor Watch, Huawei Technologies Co., Ltd., Shenzhen, China) was allowed. The patients with "possible AF" episodes using the PPG algorithm were further confirmed by health providers among the MAFA (mobile AF app) Telecare center and network hospitals, with clinical evaluation, electrocardiogram, or 24-h Holter monitoring.

resultsThere were 246,541 individuals who downloaded the PPG screening app, and 187,912 individuals used smart devices to monitor their pulse rhythm between October 26, 2018, and May 20, 2019. Among those with PPG monitoring (mean age 35 years, 86.7% male), 424 (of 187,912, 0.23%) (mean age 54 years, 87.0% male) received a "suspected AF" notification. Of those effectively followed up, 227 individuals (of 262, 87.0%) were confirmed as having AF, with the positive predictive value of PPG signals being 91.6% (95% confidential interval [CI]: 91.5% to 91.8%). Both suspected AF and identified AF markedly increased with age (p for trend <0.001), and individuals in Northeast China had the highest proportion of detected AF of 0.28% (95% CI: 0.20% to 0.39%). Of the individuals with identified AF, 216 (of 227, 95.1%) subsequently entered a program of integrated AF management using a mobile AF application; approximately 80% of high-risk patients were successfully anticoagulated.

conclusionsBased on the present study, continuous home monitoring with smart device-based PPG technology could be a feasible approach for AF screening. This would help efforts at screening and detection of AF, as well as early interventions to reduce stroke and other AF-related complications. (Mobile Health [mHealth] Technology for Improved Screening, Patient Involvement and Optimizing Integrated Care in Atrial Fibrillation [MAFA II]; ChiCTR-OOC-17014138).

Indexed as

Mobile ApplicationsAdultAgedAlgorithmsAtrial FibrillationChinaFemaleHumansMaleMiddle AgedMonitoring, AmbulatoryPhotoplethysmographySensitivity and SpecificityTelemedicineYoung Adultatrial fibrillationintegrated carephotoplethysmographyscreening

Identifiers

PMID31487545
OpenAlexW2970354537

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.