ArticleAngewandte Chemie (International ed. in English)2019
Modular Approach to Degradable Acetal Polymers Using Cascade Enyne Metathesis Polymerization.
Article in Angewandte Chemie (International ed. in English), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- Olefin Metathesis Catalyzed by a Latent Ruthenathiete Complex.Organometallics · 2026Article
- Ring-Opening Metathesis Polymerization of Levoglucosenone-Derived Enyne Monomers.Journal of polymer science (2020) · 2025Article
- Development of Bioorthogonally Degradable Tough Hydrogels Using Enamine N-Oxide Based Crosslinkers.Advanced materials (Deerfield Beach, Fla.) · 2025Article
- Cascade Alternating Metathesis Cyclopolymerization of Diynes and Dihydrofuran.ACS macro letters · 2022Article
- Biodegradable Elastomers and Gels for Elastic Electronics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Review
- Degradable polymers via olefin metathesis polymerization.Progress in polymer science · 2021Article
- Integrating Emerging Polymer Chemistries for the Advancement of Recyclable, Biodegradable, and Biocompatible Electronics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Review
- Degradable Polyphosphoramidate via Ring-Opening Metathesis Polymerization.ACS macro letters · 2020Article
- Alternating Cascade Metathesis Polymerization of Enynes and Cyclic Enol Ethers with Active Ruthenium Fischer Carbenes.Journal of the American Chemical Society · 2020Article
- Alternating Ring-Opening Metathesis Polymerization Provides Easy Access to Functional and Fully Degradable Polymers.Macromolecules · 2020Article
- Cascade polymerizations: recent developments in the formation of polymer repeat units by cascade reactions.Chemical science · 2020Review
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
A modular synthetic approach to degradable metathesis polymers is presented using acetal-containing enyne monomers. The monomers are prepared in a short and divergent synthetic sequence that features two points of modification to tune polymerization behavior and introduce molecular cargo. Steric and stereochemical elements are critical in the monomer design in order to provide rapid and living polymerizations capable of generating block polymers. The developed polyacetal materials readily undergo pH-dependent degradation in aqueous mixtures, and the rate of hydrolysis can be tuned through post-polymerization modification with triazolinedione click chemistry. This presents a new scaffold for responsive metathesis polymers that may find use in applications that requires controllable breakdown and release of small molecules.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.