Evidence map›Paper›PMID 31487153›Full record

ArticleACS infectious diseases2019

Sugar-Modified Analogs of Auranofin Are Potent Inhibitors of the Gastric Pathogen

Tessa D Epstein, Bin Wu, Karen D Moulton, Mingdi Yan, Danielle H Dube

Open access · greenAbstract read
In one paragraph

Article in ACS infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
  2. Anti-staphylococcal activity of the auranofin-analogous PEtFrontiers in cellular and infection microbiology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Metals to combat antimicrobial resistance.Nature reviews. Chemistry · 2023
    Review
  10. Article
  11. New Auranofin Analogs with Antibacterial Properties againstAntibiotics (Basel, Switzerland) · 2021
    Article
  12. Metal Complexes, an Untapped Source of Antibiotic Potential?Antibiotics (Basel, Switzerland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Tessa D EpsteinDepartment of Chemistry & Biochemistry , Bowdoin College , 6600 College Station , Brunswick , Maine 04011 , United States.
Bin WuDepartment of Chemistry , University of Massachusetts Lowell , 1 University Avenue , Lowell , Massachusetts 01854 , United States.
Karen D MoultonDepartment of Chemistry & Biochemistry , Bowdoin College , 6600 College Station , Brunswick , Maine 04011 , United States.
Mingdi YanDepartment of Chemistry , University of Massachusetts Lowell , 1 University Avenue , Lowell , Massachusetts 01854 , United States.ORCID 0000-0003-1121-4007
Danielle H DubeDepartment of Chemistry & Biochemistry , Bowdoin College , 6600 College Station , Brunswick , Maine 04011 , United States.ORCID 0000-0001-5986-8945
Bowdoin College · USUniversity of Massachusetts Lowell · US

Funding

The Maine Biomedical Research Network (INBRE)P20GM103423 · NIGMS · MOUNT DESERT ISLAND BIOLOGICAL LAB · PI Dustin Lynn Updike · 2012 to 2026
$60.0M
Deciphering Helicobacter pylori's glycocode: uncovering & harnessing drug targetsR15GM109397 · NIGMS · BOWDOIN COLLEGE · PI DUBE, DANIELLE H. · 2015 to 2021
$1.1M
Interaction and uptake of nanoparticles by bacteria mediated by unique sugarsR15GM128164 · NIGMS · UNIVERSITY OF MASSACHUSETTS LOWELL · PI YAN, MINGDI · 2018 to 2018
$455k
Glycosylated Atomically-Precise Gold Clusters: Design, Synthesis and Antimicrobial ActivityR21AI140418 · NIAID · UNIVERSITY OF MASSACHUSETTS LOWELL · PI YAN, MINGDI · 2018 to 2019
$419k
NIAID NIH HHS R21 AI140418NIGMS NIH HHS P20 GM103423NIGMS NIH HHS R15 GM109397NIGMS NIH HHS R15 GM128164
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anti-Bacterial AgentsAuranofinCell DeathDrug RepositioningEnzyme InhibitorsGoldHelicobacter InfectionsHelicobacter pyloriMicrobial Sensitivity TestsOxidative StressSugarsSulfhydryl CompoundsThioredoxin-Disulfide ReductaseAnti-Bacterial AgentsAuranofinEnzyme InhibitorsGoldSugarsSulfhydryl CompoundsThioredoxin-Disulfide ReductaseantibioticauranofinHelicobacter pyloriinhibitorsugar−gold conjugatethioredoxin

Identifiers

PMID31487153
PMCPMC7123778
OpenAlexW2972067388

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.