Evidence map›Paper›PMID 31486952›Full record

ArticleJournal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry2019

Radical S-adenosylmethionine maquette chemistry: Cx

Amanda Galambas, Jacquelyn Miller, Morgan Jones, Elizabeth McDaniel, Molly Lukes, Hope Watts, Valérie Copié, Joan B Broderick, Robert K Szilagyi, Eric M Shepard

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Protocellular Heme and Iron-Sulfur Clusters.Accounts of chemical research · 2024
    Review
  2. Article
  3. Review
  4. Changing the tracks: screening for electron transfer proteins to support hydrogen production.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2022
    Article
  5. Article
  6. HutW fromBiochemistry · 2021
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Amanda GalambasDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, MT, 59717, USA.
Jacquelyn MillerDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, MT, 59717, USA.
Morgan JonesDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, MT, 59717, USA.
Elizabeth McDanielDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, MT, 59717, USA.
Molly LukesDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, MT, 59717, USA.
Hope WattsDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, MT, 59717, USA.
Valérie CopiéDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, MT, 59717, USA.ORCID 0000-0002-2778-1463
Joan B BroderickDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, MT, 59717, USA.ORCID 0000-0001-7057-9124
Robert K SzilagyiDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, MT, 59717, USA. szilagyi@montana.edu.ORCID 0000-0002-9314-6222
Eric M ShepardDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, MT, 59717, USA. eshepard@montana.edu.
Montana State University · US

Funding

Iron-Sulfur Clusters in Biological Radical GenerationR01GM054608 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI BRODERICK, JOAN B · 2001 to 2018
$4.7M
NIGMS NIH HHS R01 GM054608
6 · The paper itself

Abstract

The synthesis and characterization of short peptide-based maquettes of metalloprotein active sites facilitate an inquiry into their structure/function relationships and evolution. The [4Fe-4S]-maquettes of bacterial ferredoxin metalloproteins (Fd) have been used in the past to engineer redox active centers into artificial metalloenzymes. The novelty of our study is the application of maquettes to the superfamily of [4Fe-4S] cluster and S-adenosylmethionine-dependent radical metalloenzymes (radical SAM). The radical SAM superfamily enzymes contain site-differentiated, redox active [4Fe-4S] clusters coordinated to Cx

Indexed as

C-PeptideCysteineFerredoxinsIron-Sulfur ProteinsS-AdenosylmethionineC-PeptideCysteineFerredoxinsIron-Sulfur ProteinsS-Adenosylmethionine[4Fe–4S]-maquettesCysteine motifsElectron paramagnetic resonance spectroscopyFerredoxinIron sulfur clustersProtoenzymesRadical S-adenosylmethionineUV–Vis spectroscopy

Identifiers

PMID31486952
OpenAlexW2971397926

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.