Evidence map›Paper›PMID 31486675›Full record

ArticleAmerican journal of respiratory cell and molecular biology2020

Epithelial Expression of YAP and TAZ Is Sequentially Required in Lung Development.

Hideaki Isago, Akihisa Mitani, Yu Mikami, Masafumi Horie, Hirokazu Urushiyama, Ryuji Hamamoto, Yasuhiro Terasaki, Takahide Nagase

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Article in American journal of respiratory cell and molecular biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

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  11. Three-Dimensional Bioprinting of an In Vitro Lung Model.International journal of molecular sciences · 2023
    Article
  12. Innate immune responses in pneumonia.Pneumonia (Nathan Qld.) · 2023
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Hideaki IsagoDepartment of Respiratory Medicine, University of Tokyo Graduate School of Medicine, Tokyo, Japan.
Akihisa MitaniDepartment of Respiratory Medicine, University of Tokyo Graduate School of Medicine, Tokyo, Japan.
Yu MikamiDepartment of Respiratory Medicine, University of Tokyo Graduate School of Medicine, Tokyo, Japan.
Masafumi HorieDepartment of Respiratory Medicine, University of Tokyo Graduate School of Medicine, Tokyo, Japan.
Hirokazu UrushiyamaDepartment of Respiratory Medicine, University of Tokyo Graduate School of Medicine, Tokyo, Japan.
Ryuji HamamotoDivision of Molecular Modification and Cancer Biology, National Cancer Center Research Institute, Tokyo, Japan; and.
Yasuhiro TerasakiDepartment of Analytic Human Pathology, Nippon Medical School, Tokyo, Japan.
Takahide NagaseDepartment of Respiratory Medicine, University of Tokyo Graduate School of Medicine, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

TAZ (transcriptional coactivator with PDZ-binding motif) and YAP (Yes-associated protein) are key molecules of the Hippo pathway. Recent studies revealed that these molecules are essential in lung development; however, the precise signaling cascade involving these molecules and the differences in their roles during lung development remain unknown. We aimed to investigate YAP and TAZ functions using lung epithelium-specific

Indexed as

Adaptor Proteins, Signal TransducingAnimalsCell Cycle ProteinsHedgehog ProteinsIntracellular Signaling Peptides and ProteinsLungMice, KnockoutOrganogenesisPhosphoproteinsProtein Serine-Threonine KinasesProto-Oncogene Proteins c-yesTrans-ActivatorsAdaptor Proteins, Signal TransducingCell Cycle ProteinsHedgehog ProteinsIntracellular Signaling Peptides and ProteinsPhosphoproteinsProtein Serine-Threonine KinasesProto-Oncogene Proteins c-yesTrans-ActivatorsWwtr1 protein, mousealveolarizationbronchial morphogenesisfibroblast growth factor 10Hippo signaling pathwaysonic hedgehog

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.