Evidence map›Paper›PMID 31486162›Full record

ArticlePediatric diabetes2019

The association of sleep disturbances with glycemia and obesity in youth at risk for or with recently diagnosed type 2 diabetes.

Babak Mokhlesi, Karla A Temple, Ashley H Tjaden, Sharon L Edelstein, Kristen J Nadeau, Tamara S Hannon, Shalini Manchanda, Susan Sam, Elena Barengolts, Kristina M Utzschneider and 3 more

Open access · greenAbstract read
In one paragraph

Article in Pediatric diabetes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

Babak MokhlesiUniversity of Chicago, Chicago, Illinois.ORCID 0000-0001-8135-5433
Karla A TempleUniversity of Chicago, Chicago, Illinois.
Ashley H TjadenGeorge Washington University Biostatistics Center (RISE Coordinating Center), Rockville, Maryland.
Sharon L EdelsteinGeorge Washington University Biostatistics Center (RISE Coordinating Center), Rockville, Maryland.ORCID 0000-0001-8457-4404
Kristen J NadeauUniversity of Colorado Anschutz Medical Campus/Children's Hospital Colorado, Denver, Colorado.
Tamara S HannonIndiana University School of Medicine, Indianapolis, Indiana.ORCID 0000-0002-8792-4278
Shalini ManchandaIndiana University School of Medicine, Indianapolis, Indiana.
Susan SamUniversity of Chicago, Chicago, Illinois.
Elena BarengoltsJesse Brown VA Medical Center, Chicago, Illinois.
Kristina M UtzschneiderVA Puget Sound Health Care System and University of Washington, Seattle, Washington.
David A EhrmannUniversity of Chicago, Chicago, Illinois.
Eve Van CauterUniversity of Chicago, Chicago, Illinois.
RISE Consortium
University of Chicago · USGeorge Washington University · USIndiana University School of MedicineChildren's Hospital Colorado · USJesse Brown VA Medical Center · USUniversity of Washington · US

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR001857 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2016 to 2025
$129.3M
Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Southern California Clinical and Translational Science InstituteUL1TR001855 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Thomas A Buchanan, Michele D. Kipke · 2016 to 2026
$81.3M
Colorado Clinical and Translational Sciences InstituteUL1TR001082 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2013 to 2017
$48.0M
Yale Diabetes Research CenterP30DK045735 · NIDDK · YALE UNIVERSITY · PI Kevan C Herold, GERALD I SHULMAN · 1993 to 2026
$44.0M
Vector and Transgenic Mouse CoreP30DK017047 · NIDDK · UNIVERSITY OF WASHINGTON · PI Tomas Vaisar · 1986 to 2026
$41.4M
Indiana Clinical and Translational Sciences InstituteUL1TR001108 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI DENNE, SCOTT C., SHEKHAR, ANANTHA · 2013 to 2017
$23.3M
Pilot and Feasibility ProgramP30DK020595 · NIDDK · UNIVERSITY OF CHICAGO · PI Raghavendra G Mirmira · 2013 to 2026
$20.9M
Re-Engineering Translational Research at the University of ChicagoUL1TR000430 · NCATS · UNIVERSITY OF CHICAGO · PI SOLWAY, JULIAN · 2012 to 2016
$20.2M
Translation CoreP30DK097512 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI Carmella Evans-Molina · 2015 to 2026
$17.4M
NRSA Training CoreTL1TR001858 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI RADOMSKI, THOMAS, RUBIO, DORIS M · 2016 to 2025
$11.1M
Research Design, Data, and Analytics CoreP30DK092949 · NIDDK · UNIVERSITY OF CHICAGO · PI Ronald T. Ackermann, MARSHALL H CHIN · 2011 to 2026
$10.0M
NCATS NIH HHS TL1 TR001858NCATS NIH HHS UL1 TR000430NCATS NIH HHS UL1 TR001082NCATS NIH HHS UL1 TR001108NCATS NIH HHS UL1 TR001855NCATS NIH HHS UL1 TR001857NCATS NIH HHS UL1 TR001863NHLBI NIH HHS K24 HL145076NHLBI NIH HHS R01 HL119161NHLBI NIH HHS R01HL119161NHLBI NIH HHS T32 HL007909NIDDK NIH HHS P30 DK017047NIDDK NIH HHS P30-DK-017047NIDDK NIH HHS P30 DK020595NIDDK NIH HHS P30-DK-020595NIDDK NIH HHS P30 DK045735NIDDK NIH HHS P30-DK-045735NIDDK NIH HHS P30 DK092949NIDDK NIH HHS P30 DK097512NIDDK NIH HHS P30-DK-097512NIDDK NIH HHS U01 DK094406NIDDK NIH HHS U01-DK-094406NIDDK NIH HHS U01 DK094430NIDDK NIH HHS U01-DK-094430NIDDK NIH HHS U01 DK094431NIDDK NIH HHS U01-DK-094431NIDDK NIH HHS U01 DK094438NIDDK NIH HHS U01-DK-094438NIDDK NIH HHS U01 DK094467NIDDK NIH HHS U01-DK-094467NIH HHS UL1-TR-000430NIH HHS UL1-TR-001082NIH HHS UL1-TR-001108NIH HHS UL1-TR-001855NIH HHS UL1-TR-001857NIH HHS UL1-TR-001858NIH HHS UL1-TR-001863VA
6 · The paper itself

Abstract

objectivePoor sleep may increase obesity and type 2 diabetes (T2D) risk in youth. We explored whether subjective sleep duration, sleep quality, or risk for obstructive sleep apnea (OSA) are associated with glycemia, body mass index (BMI), or blood pressure (BP) in overweight/obese youth.

methodsTwo-hundred and fourteen overweight/obese youth of 10 to 19 years of age at risk for or recently diagnosed with T2D who were screened for the Restoring Insulin Secretion (RISE) Study had a 2-hour oral glucose tolerance test (OGTT) and completed a Cleveland Adolescent Sleepiness questionnaire and a Sleep Disturbances Scale questionnaire. Independent associations between sleep variables and measures of glycemia, BMI, and BP were evaluated with regression models.

resultsThe multiethnic cohort was 67% female, 14.1 ± 2.1 years, and BMI 35.9 ± 6.5 kg/m

conclusionsIn overweight/obese youth with or at risk for T2D, daytime sleepiness was associated with higher HbA1c. In addition, poor sleep quality and OSA risk were associated with higher BMI. These findings support intervention studies aimed at improving sleep quality in obese youth.

Indexed as

Blood GlucoseSleepAdolescentChildDiabetes Mellitus, Type 2FemaleHumansMaleObesitySleep Apnea, ObstructiveBlood Glucoseadolescentschildrenglucoseglycemiahemoglobin A1chypersomnolencehypertensionobesitysleep apneasleep durationsleepinesssleep quality

Identifiers

PMID31486162
PMCPMC7199716
OpenAlexW2972222885

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.