Evidence map›Paper›PMID 31485950›Full record

ArticleJournal of applied genetics2019

Decreased neural stem cell proliferation and olfaction in mouse models of Niemann-Pick C1 disease and the response to hydroxypropyl-β-cyclodextrin.

Jessica Dragotto, Giampiero Palladino, Sonia Canterini, Paola Caporali, Rutaraj Patil, Maria Teresa Fiorenza, Robert P Erickson

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Journal of applied genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Jessica DragottoDivision of Neuroscience, Department of Psychology, Università La Sapienza di Roma, Rome, Italy.
Giampiero PalladinoDivision of Neuroscience, Department of Psychology, Università La Sapienza di Roma, Rome, Italy.
Sonia CanteriniDivision of Neuroscience, Department of Psychology, Università La Sapienza di Roma, Rome, Italy.
Paola CaporaliDivision of Neuroscience, Department of Psychology, Università La Sapienza di Roma, Rome, Italy.
Rutaraj PatilDepartment of Pediatrics, University of Arizona School of Medicine, Tucson, AZ, 85724-5073, USA.
Maria Teresa FiorenzaDivision of Neuroscience, Department of Psychology, Università La Sapienza di Roma, Rome, Italy.
Robert P EricksonDepartment of Pediatrics, University of Arizona School of Medicine, Tucson, AZ, 85724-5073, USA. erickson@peds.arizona.edu.ORCID http://orcid.org/0000-0002-5298-5038
Sapienza University of Rome · ITUniversity of Arizona · USFondazione Santa Lucia · IT

Funding

Fondazione Telethon GGP13183
6 · The paper itself

Abstract

The Npc1

Indexed as

2-Hydroxypropyl-beta-cyclodextrinAdministration, IntranasalAnimalsCell ProliferationCholesterolDisease Models, AnimalHumansIntracellular Signaling Peptides and ProteinsMiceNeural Stem CellsNiemann-Pick C1 ProteinNiemann-Pick Disease, Type CSmell2-Hydroxypropyl-beta-cyclodextrinCholesterolIntracellular Signaling Peptides and ProteinsNiemann-Pick C1 ProteinNpc1 protein, mouseHydroxypropyl-beta-cyclodextrinsNasal deliveryNeural stem cellsNiemann–Pick C1 diseaseOlfaction

Identifiers

PMID31485950
OpenAlexW2971876616

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.