ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2020
From contamination to infective endocarditis-a population-based retrospective study of Corynebacterium isolated from blood cultures.
Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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39 citing papers in PubMed, 51 citations in OpenAlex.
- Newly recognized typical microorganisms in intracardiac prosthetic material-related infective endocarditis: evidence behind their inclusion in the 2023 Duke-ISCVID criteria.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026Review
- Clinical outcomes of teicoplanin for Corynebacterium species bacteremia: A retrospective observational study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026Article
- Epidemiological and molecular characterization of multidrug-resistantMicrobiology spectrum · 2026Article
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- Corynebacterium Striatum Native Valve Endocarditis.Pakistan journal of medical sciences · 2026Article
- Clinical and Epidemiologic Characteristics of Anaerobic Bacteria Originating from Blood Cultures: A Five-Year Retrospective Study.Infection and drug resistance · 2026Article
- A Case ofCase reports in cardiology · 2026Article
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- Clinical characteristics, antimicrobial resistance patterns, and outcomes of Corynebacterium bacteremia: a 15-year retrospective study.BMC infectious diseases · 2025Article
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- Genomic epidemiology and antimicrobial resistance ofJournal of clinical microbiology · 2025Article
- Microbiota of Healthy Dental Pulp Under the Omics Loupe.International journal of molecular sciences · 2025Article
- Retrospective analysis of antimicrobial susceptibility profiles of non-Journal of clinical microbiology · 2024Article
- Comparison of bloodstream infections due to Corynebacterium striatum, MRSA, and MRSE.BMC infectious diseases · 2024Article
- Corynebacterium striatum-Induced Native Valve Infective Endocarditis in an Immunocompetent Patient.Cureus · 2024Article
- Outcome of Corynebacterial Bloodstream Infection in Patients With Cardiac Implantable Electronic Devices: A Brief Report and Systematic Review.Open forum infectious diseases · 2024Article
- Infective Endocarditis Due toMicroorganisms · 2024Review
- Automated titanium fastener for surgical aortic valve replacement-preventive role for infective endocarditis?European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2024Article
- The first case of urosepsis caused byFuture microbiology · 2024Article
- Even a single positive blood culture may matter - A case of prosthetic valve infective endocarditis caused byIDCases · 2024Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Corynebacterium is a genus that can contaminate blood cultures and also cause severe infections like infective endocarditis (IE). Our purpose was to investigate microbiological and clinical features associated with contamination and true infection. A retrospective population-based study of Corynebacterium bacteremia 2012-2017 in southern Sweden was performed. Corynebacterium isolates were species determined using a matrix-assisted laser desorption/ionization-time-of-flight mass spectrometry (MALDI-TOF MS). Patient were, from the medical records, classified as having true infection or contamination caused by Corynebacterium through a scheme considering both bacteriological and clinical features and the groups were compared. Three hundred thirty-nine episodes of bacteremia with Corynebacterium were identified in 335 patients of which 30 (8.8%) episodes were classified as true infection. Thirteen patients with true bacteremia had only one positive blood culture. Infections were typically community acquired and affected mostly older males with comorbidities. The focus of infection was most often unknown, and in-hospital mortality was around 10% in both the groups with true infection and contamination. Corynebacterium jeikeium and Corynebacterium striatum were significantly overrepresented in the group with true infection, whereas Corynebacterium afermentans was significantly more common in the contamination group. Eight episodes of IE were identified, all of which in patients with heart valve prosthesis. Six of the IE cases affected the aortic valve and six of seven patients were male. The species of Corynebacterium in blood cultures can help to determine if a finding represent true infection or contamination. The finding of a single blood culture with Corynebacterium does not exclude true infection such as IE.
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