Evidence map›Paper›PMID 31485716›Full record

ReviewCellular and molecular life sciences : CMLS2020

Insights from Drosophila on mitochondrial complex I.

Shauna-Kay Rhooms, Anjaneyulu Murari, Naga Sri Vidya Goparaju, Maximino Vilanueva, Edward Owusu-Ansah

Open access · greenAbstract readReview
In one paragraph

Review in Cellular and molecular life sciences : CMLS, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. A new metabolic model ofLife science alliance · 2023
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Fourth Report on Chicken Genes and Chromosomes 2022.Cytogenetic and genome research · 2022
    Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Shauna-Kay RhoomsDepartment of Physiology and Cellular Biophysics, Columbia University Medical Center, New York, NY, 10032, USA.
Anjaneyulu MurariDepartment of Physiology and Cellular Biophysics, Columbia University Medical Center, New York, NY, 10032, USA.
Naga Sri Vidya GoparajuDepartment of Physiology and Cellular Biophysics, Columbia University Medical Center, New York, NY, 10032, USA.
Maximino VilanuevaDepartment of Physiology and Cellular Biophysics, Columbia University Medical Center, New York, NY, 10032, USA.
Edward Owusu-AnsahDepartment of Physiology and Cellular Biophysics, Columbia University Medical Center, New York, NY, 10032, USA. eo2364@cumc.columbia.edu.ORCID http://orcid.org/0000-0002-3451-1752
Columbia University Irving Medical Center · US

Funding

Identifying Remote Regulators of Complex I Biogenesis in DrosophilaR35GM124717 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI OWUSU-ANSAH, EDWARD · 2017 to 2021
$2.2M
IGFBP-Mediated Local and Systemic Effects of Mitochondrial Dysfunction in Skeletal MusclesR21DK112074 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI OWUSU-ANSAH, EDWARD · 2016 to 2018
$594k
Genetic Dissection of OXPHOS Assembly in Skeletal MusclesR21AR077312 · NIAMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI OWUSU-ANSAH, EDWARD · 2020 to 2021
$387k
NIAMS NIH HHS R21 AR077312NIDDK NIH HHS R21 DK112074NIGMS NIH HHS GM124717NIGMS NIH HHS R35 GM124717
6 · The paper itself

Abstract

nadhubiquinone oxidoreductase, more commonly referred to as mitochondrial complex I (CI), is the largest discrete enzyme of the oxidative phosphorylation system (OXPHOS). It is localized to the mitochondrial inner membrane. CI oxidizes NADH generated from the tricarboxylic acid cycle to NAD

Indexed as

AnimalsDrosophilaDrosophila ProteinsElectron Transport Complex IMitochondriaOxidative PhosphorylationProtein SubunitsDrosophila ProteinsElectron Transport Complex IProtein SubunitsComplex I assemblyDrosophilaMitochondriaNADH:ubiquinone oxidoreductaseOXPHOSSupercomplex

Identifiers

PMID31485716
PMCPMC7289077
OpenAlexW2971376835

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.