Evidence map›Paper›PMID 31485679›Full record

ArticleSkeletal radiology2020

CT-guided transarticular biopsy of the sacroiliac joint: Technique and histomorphological results. A preliminary study.

Niels Egund, Flemming Brandt Sørensen, René Østgård, Anne Gitte Loft, Lene Warner Thorup Boel, Anne Grethe Jurik

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In one paragraph

Article in Skeletal radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact, top 83% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
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  3. CD200Nature communications · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Niels EgundDepartment of Radiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 35, Entrance C, location C118/ reference point C109, 8200, Aarhus N, Denmark.ORCID https://orcid.org/0000-0002-5957-6368
Flemming Brandt SørensenDepartment of Pathology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, Aarhus, Denmark.ORCID https://orcid.org/0000-0002-5446-1035
René ØstgårdDepartment of Rheumatology, Regional Hospital, Silkeborg, Falkevej 1G, 8600, Silkeborg, Denmark.ORCID https://orcid.org/0000-0001-6124-8972
Anne Gitte LoftDepartment of Rheumatology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, Aarhus, Denmark.ORCID https://orcid.org/0000-0001-6374-841X
Lene Warner Thorup BoelDepartment of Forensic Medicine, Aarhus University, Palle Juul-Jensens Boulevard 99, Aarhus, Denmark.ORCID https://orcid.org/0000-0002-4654-6960
Anne Grethe JurikDepartment of Radiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 35, Entrance C, location C118/ reference point C109, 8200, Aarhus N, Denmark. annejuri@rm.dk.ORCID https://orcid.org/0000-0003-2571-0466
Aarhus University Hospital · DKAarhus University · DKRegionshospitalet Silkeborg · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo introduce and evaluate computed tomography (CT)-guided transarticular needle biopsy of the cartilaginous sacroiliac joint (SIJ) and to assess the biopsy results microscopically. MATERIALS AND

methodsThe new CT-guided transarticular biopsy of the SIJ was performed in a young corpse and ten patients, two males and eight females aged 18-81 years. All patients had abnormal findings by magnetic resonance imaging (MRI) of the SIJs, including bone marrow edema, related to different types of joint disorders. The biopsies were focused on areas with bone marrow edema. The quality of the specimens obtained, using two different types of biopsy needles, was assessed microscopically.

resultsBiopsies containing cartilage, subchondral plate, and bone marrow from the iliac and sacral sides were obtained from the corpse and three patients and from the iliac bone only in two patients. In three patients, the biopsy needles could not penetrate the bone marrow to the joint facet due to pronounced subchondral sclerosis, but adequate marrow biopsies were obtained. Two biopsies were inadequate, one due to technical problems and one was crushed during preparation. Histological assessment of eight adequate specimens revealed inflammatory bone marrow changes, except in two specimens from females with pronounced sclerosis conforming to osteitis condensans ilii.

conclusionsTransarticular SIJ biopsies are obtainable and can be directed towards areas with MRI abnormalities. They can be used to confirm inflammatory changes histologically. With the biopsy needles used, severe bone marrow sclerosis may hinder penetration to the cartilage, but bone marrow specimens can be obtained.

Indexed as

Image-Guided BiopsyTomography, X-Ray ComputedAdolescentAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedSacroiliac JointBiopsyComputed tomographyHistopathologySacroiliac jointsSpondyloarthritis

Identifiers

PMID31485679
OpenAlexW2971890025

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.