ReviewMayo Clinic proceedings. Innovations, quality & outcomes2019
Clinical Manifestations, Diagnosis, and Treatment of Sarcoidosis.
Review in Mayo Clinic proceedings. Innovations, quality & outcomes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 142 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
142 citing papers in PubMed, 1 synthesis or guideline pooled it, 287 citations in OpenAlex.
- Sarcoidosis as an Autoimmune Disease.Frontiers in immunology · 2019Pooled it
- Proof-of-concept PET imaging of pulmonary sarcoidosis using VAP-1-targeted radiotracer [Respiratory research · 2025Trial
- Systemic Sarcoidosis With Neurosarcoidosis and Obstructive Hydrocephalus: A Radiologic-Pathologic Case Report.Journal of medical cases · 2026Article
- Vertebral Sarcoidosis Mimicking Metastatic Disease in a Patient With Prior Melanoma: A Diagnostic Challenge.Cureus · 2026Article
- Article
- Hepatic Sarcoidosis Unmasked by Chronic Pruritus and Esophageal Varices: A Case Report.Clinical case reports · 2026Article
- Hypopituitarism Revealing Probable Neurosarcoidosis: A Case Report and Diagnostic Challenges.Reports (MDPI) · 2026Article
- Article
- Uncovering Sex and Gender Differences in Sarcoidosis: A Systematic Review of Current Evidence.Journal of personalized medicine · 2026Review
- Diagnostic value of neutrophil-to-lymphocyte, platelet-to-lymphocyte, and lymphocyte-to-monocyte ratios for assessing organ and multiorgan involvement in sarcoidosis: a retrospective single-center study.Frontiers in medicine · 2026Article
- An Unusual Cause of Cast Nephropathy in a Patient Presenting With Hypercalcemia and Renal Failure: A Case Report.Cureus · 2026Article
- Article
- Exploring sarcoidosis via nailfold capillaroscopy: A window into the disease's microvascular landscape.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2025Article
- A Rare Presentation of Renal Sarcoidosis with Severe, Recurrent Hypercalcemia Despite Low-normal Vitamin D Levels.JCEM case reports · 2025Article
- Unmasking Sarcoidosis: Fever and Arthralgia Revealing an Underlying Granulomatous Disease.Cureus · 2025Article
- Early Optic Nerve Symptoms in Neurosarcoidosis: A Clinical Case Review.Clinical case reports · 2025Article
- Advanced Pulmonary Sarcoidosis: Treatment and Monitoring.Diagnostics (Basel, Switzerland) · 2025Review
- Article
- Article
- Diagnosis of cardiac sarcoidosis using glucose metabolic rate from four-dimensionalAnnals of nuclear medicine · 2025Article
82 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The focus of this review is current knowledge about the epidemiology, clinical manifestations, diagnosis, and treatment of both pulmonary sarcoidosis and extrapulmonary sarcoidosis. Although intrathoracic involvement is the hallmark of the disease, present in over 90% of patients, sarcoidosis can affect virtually any organ. Clinical presentations of sarcoidosis are diverse, ranging from asymptomatic, incidental findings to organ failure. Diagnosis requires the presence of noncaseating granuloma and compatible presentations after exclusion of other identifiable causes. Spontaneous remission is frequent, so treatment is not always indicated unless the disease is symptomatic or causes progressive organ damage/dysfunction. Glucocorticoids are the cornerstone of treatment of sarcoidosis even though evidence from randomized controlled studies is lacking. Glucocorticoid-sparing agents and biologic agents are often used as second- and third-line therapy for patients who do not respond to glucocorticoids or experience serious adverse effects.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.