Evidence map›Paper›PMID 31485460›Full record

ReviewJournal of immunology research2019

Immunomodulation of CXCL10 Secretion by Hepatitis C Virus: Could CXCL10 Be a Prognostic Marker of Chronic Hepatitis C?

Silvia Martina Ferrari, Poupak Fallahi, Ilaria Ruffilli, Giusy Elia, Francesca Ragusa, Sabrina Rosaria Paparo, Armando Patrizio, Valeria Mazzi, Michele Colaci, Dilia Giuggioli and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Journal of immunology research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 61 citations in OpenAlex.

  1. Review
  2. Review
  3. Olink proteomics and lipidomics analysis of serum from patients infected with non-tuberculous mycobacteria and Mycobacterium tuberculosis.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. CXCL9-11 chemokines and CXCR3 receptor in teleost fish species.Fish and shellfish immunology reports · 2022
    Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Silvia Martina FerrariDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Poupak FallahiDepartment of Translational Research and of New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
Ilaria RuffilliDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Giusy EliaDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Francesca RagusaDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Sabrina Rosaria PaparoDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Armando PatrizioDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Valeria MazziDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Michele ColaciInternal Medicine Unit, Cannizzaro Hospital, Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy.ORCID https://orcid.org/0000-0002-3606-3404
Dilia GiuggioliRheumatology Unit, Azienda Ospedaliero-Universitaria di Modena, University of Modena and Reggio Emilia, Modena, Italy.
Clodoveo FerriRheumatology Unit, Azienda Ospedaliero-Universitaria di Modena, University of Modena and Reggio Emilia, Modena, Italy.
Alessandro AntonelliDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.ORCID https://orcid.org/0000-0002-5211-6342
University of Pisa · ITUniversity of Modena and Reggio Emilia · ITUniversity of Catania · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemokine (C-X-C motif) ligand (CXCL)10 and other CXCR3 chemokines are involved in the pathogenesis of acute and "chronic hepatitis C virus (HCV) infection" (CHC). Here, we review the scientific literature about HCV and CXCL10. The combination of circulating CXCL10 and single nucleotide polymorphisms (SNPs) in IL-28B can identify patients with acute HCV infection most likely to undergo spontaneous HCV clearance and those in need of early antiviral therapy. In CHC, the HCV and intrahepatic interferon- (IFN-)

Indexed as

Acute DiseaseAntiviral AgentsChemokine CXCL10Hepatitis CHepatitis C, ChronicHumansImmunomodulationInterferon-alphaInterferon-gammaInterferon LambdaInterferonsInterleukinsLiverPolymorphism, Single NucleotidePrognosisReceptors, CXCR3Antiviral AgentsChemokine CXCL10CXCR3 protein, humanInterferon-alphaInterferon-gammaInterferon Lambdainterferon-lambda, humanInterferonsInterleukinsReceptors, CXCR3Ribavirin

Identifiers

PMID31485460
PMCPMC6702819
OpenAlexW2964835591

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.