Evidence map›Paper›PMID 31485381›Full record

ArticleProceedings of the ... AAAI Conference on Artificial Intelligence. AAAI Conference on Artificial Intelligence

A Powerful Global Test Statistic for Functional Statistical Inference.

Jingwen Zhang, Joseph Ibrahim, Tengfei Li, Hongtu Zhu

Abstract read
In one paragraph

Article in Proceedings of the ... AAAI Conference on Artificial Intelligence. AAAI Conference on Artificial Intelligence. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jingwen ZhangDepartment of Biostatistics, UNC Gillings School of Global Public Health, University of North Carolina at Chapel Hill.
Joseph IbrahimDepartment of Biostatistics, UNC Gillings School of Global Public Health, University of North Carolina at Chapel Hill.
Tengfei LiBiomedical Research Imaging Center, UNC School of Medicine, University of North Carolina at Chapel Hill.
Hongtu ZhuDepartment of Biostatistics, UNC Gillings School of Global Public Health, University of North Carolina at Chapel Hill.

Funding

Statistical Analysis of Biomedical Imaging Data in Curved SpaceR01MH086633 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI IBRAHIM, JOSEPH G · 2010 to 2018
$2.9M
Analysis of Big Data Squared in Biomedical StudiesR01MH116527 · NIMH · YALE UNIVERSITY · PI ZHANG, HEPING · 2018 to 2022
$2.3M
NIMH NIH HHS R01 MH086633NIMH NIH HHS R01 MH116527
6 · The paper itself

Abstract

We consider the problem of performing an association test between functional data and scalar variables in a varying coefficient model setting. We propose a functional projection regression model and an associated global test statistic to aggregate relatively weak signals across the domain of functional data, while reducing the dimension. An optimal functional projection direction is selected to maximize signal-to-noise ratio with ridge penalty. Theoretically, we systematically study the asymptotic distribution of the global test statistic and provide a strategy to adaptively select the optimal tuning parameter. We use simulations to show that the proposed test outperforms all existing state-of-the-art methods in functional statistical inference. Finally, we apply the proposed testing method to the genome-wide association analysis of imaging genetic data in UK Biobank dataset.

Identifiers

PMID31485381
PMCPMC6724542

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.