ArticleMaternal health, neonatology and perinatology2019
Intact cord resuscitation versus early cord clamping in the treatment of depressed newborn infants during the first 10 minutes of birth (Nepcord III) - a randomized clinical trial.
Article in Maternal health, neonatology and perinatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 51 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Early or Late Cord Clamping in the Depressed Neonate - a Randomized Controlled Study in a Low-income Facility Setting for Improved Early Neonatal Outcome
SAVE (Sustained Cord Circulation Awaiting VEntilation)
Who cites it
51 citing papers in PubMed, 2 syntheses or guidelines pooled it, 94 citations in OpenAlex.
- 2025 Korean Guidelines for Cardiopulmonary Resuscitation: Part 9. Neonatal resuscitation.Clinical and experimental emergency medicine · 2026Guideline
- Umbilical cord management in newborn resuscitation: a systematic review and meta-analysis.Pediatric research · 2025Pooled it
- Effect of intact cord resuscitation versus conventional cord clamping on clinical outcomes in very preterm neonates: a randomized controlled trial from Eastern India.European journal of pediatrics · 2026Trial
- Cardiac and cerebral hemodynamics with umbilical cord milking compared with early cord clamping: A randomized cluster crossover trial.Early human development · 2023Trial
- Trial
- Parental Acceptability and Experiences of In-Bed Resuscitation at Birth: Findings From a Cross-Sectional Survey.Journal of pediatrics. Clinical practice · 2026Article
- Care of the Newborn and Cord During the Third Stage of Labour (Scientific Impact Paper No. 78).BJOG : an international journal of obstetrics and gynaecology · 2026Review
- Advanced Resuscitation with an Intact Cord in Preterm Lambs: A Feasibility Trial.Children (Basel, Switzerland) · 2026Article
- Stimulate, Ventilate Collaborate-A Qualitative Study Underpinning the Development of an Educational Guide to Newborn Resuscitation for Midwifery Students.Nursing open · 2026Article
- A non-invasive diagnostic tool for the assessment of optimal positive-end expiratory pressure (PEEPJournal of perinatology : official journal of the California Perinatal Association · 2026Article
- Feasibility and early outcomes of intact cord resuscitation without special equipment in extremely preterm infants born at 23-25 weeks of gestation: A case series.European journal of pediatrics · 2025Article
- Optimal Duration of Umbilical Cord Clamping with Ventilation in a Preterm Asphyxiated Ovine Model.Children (Basel, Switzerland) · 2025Article
- The Utility of Umbilical Cord Pulse Oximetry-A Translational Study with Four Minutes of Deferred Cord Clamping Using an Asphyxiated Preterm Ovine Model.Children (Basel, Switzerland) · 2025Article
- How Delayed Cord Clamping Saves Newborn Lives.Children (Basel, Switzerland) · 2025Review
- Article
- Article
- En Caul Cesarean Delivery-A Safer Way to Deliver a Premature Newborn? Narrative Review.Journal of clinical medicine · 2024Review
- Is It Possible to Perform Quality Neonatal CPR While Maintaining Skin-to-Skin Contact? A Crossover Simulation Study.Children (Basel, Switzerland) · 2024Article
- Revolutionizing Neonatal Care: A Comprehensive Review of Intact Cord Resuscitation in Newborns.Cureus · 2024Review
- Oxygen saturation and heart rate in healthy term and late preterm infants with delayed cord clamping.Pediatric research · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundExperiments have shown improved cardiovascular stability in lambs if umbilical cord clamping is postponed until positive pressure ventilation is started. Studies on intact cord resuscitation on human term infants are sparse. The purpose of this study was to evaluate differences in clinical outcomes in non-breathing infants between groups, one where resuscitation is initiated with an intact umbilical cord (intervention group) and one group where cord clamping occurred prior to resuscitation (control group).
methodsRandomized controlled trial, inclusion period April to August 2016 performed at a tertiary hospital in Kathmandu, Nepal. Late preterm and term infants born vaginally, non-breathing and in need of resuscitation according to the 'Helping Babies Breathe' algorithm were randomized to intact cord resuscitation or early cord clamping before resuscitation. Main outcome measures were saturation by pulse oximetry (SpO
resultsAt 10 minutes after birth, SpO
conclusionsThis study provides new and important information on the effects of resuscitation with an intact umbilical cord. The findings of improved SpO
trial registrationClinicaltrials.gov NCT02727517, 2016/4/4.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.