Evidence map›Paper›PMID 31485326›Full record

ArticleTranslational neurodegeneration2019

Longitudinal diffusion tensor magnetic resonance imaging analysis at the cohort level reveals disturbed cortical and callosal microstructure with spared corticospinal tract in the

Hans-Peter Müller, David Brenner, Francesco Roselli, Diana Wiesner, Alireza Abaei, Martin Gorges, Karin M Danzer, Albert C Ludolph, William Tsao, Philip C Wong and 3 more

Abstract read
In one paragraph

Article in Translational neurodegeneration, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Social Reward Learning Deficits and Concordant Brain Alterations in Rats Overexpressing Disrupted-in-Schizophrenia 1 (DISC1).The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  4. Modelling amyotrophic lateral sclerosis in rodents.Nature reviews. Neuroscience · 2022
    Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Severe white matter damage in SHANK3 deficiency: a human and translational study.Annals of clinical and translational neurology · 2020
    Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Hans-Peter Müller1Department of Neurology, University of Ulm, Oberer Eselsberg 45, RKU, D-89081 Ulm, Germany.
David Brenner1Department of Neurology, University of Ulm, Oberer Eselsberg 45, RKU, D-89081 Ulm, Germany.
Francesco Roselli1Department of Neurology, University of Ulm, Oberer Eselsberg 45, RKU, D-89081 Ulm, Germany.
Diana Wiesner1Department of Neurology, University of Ulm, Oberer Eselsberg 45, RKU, D-89081 Ulm, Germany.
Alireza Abaei3Core Facility Small Animal MRI, University of Ulm, Ulm, Germany.
Martin Gorges1Department of Neurology, University of Ulm, Oberer Eselsberg 45, RKU, D-89081 Ulm, Germany.
Karin M Danzer1Department of Neurology, University of Ulm, Oberer Eselsberg 45, RKU, D-89081 Ulm, Germany.
Albert C Ludolph1Department of Neurology, University of Ulm, Oberer Eselsberg 45, RKU, D-89081 Ulm, Germany.
William Tsao4Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, USA.
Philip C Wong4Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, USA.
Volker Rasche3Core Facility Small Animal MRI, University of Ulm, Ulm, Germany.
Jochen H Weishaupt1Department of Neurology, University of Ulm, Oberer Eselsberg 45, RKU, D-89081 Ulm, Germany.
Jan Kassubek1Department of Neurology, University of Ulm, Oberer Eselsberg 45, RKU, D-89081 Ulm, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn vivo diffusion tensor imaging (DTI) of the mouse brain was used to identify TDP-43 associated alterations in a mouse model for amyotrophic lateral sclerosis (ALS).

methodsTen mice with

resultsAlterations at the cohort level in

conclusionDTI mapping of

Indexed as

Amyotrophic lateral sclerosisDiffusion tensor imagingFiber trackingMouse brainMutant TDP-43

Identifiers

PMID31485326
PMCPMC6716821

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.