Evidence map›Paper›PMID 31485282›Full record

Trial reportCanadian respiratory journal2019

Comparison of Auto- and Fixed-Continuous Positive Airway Pressure on Air Leak in Patients with Obstructive Sleep Apnea: Data from a Randomized Controlled Trial.

Marius Lebret, Marie-Caroline Rotty, Cyril Argento, Jean-Louis Pepin, Renaud Tamisier, François Arbib, Dany Jaffuel, Nicolas Molinari, Jean-Christian Borel

Open access · goldAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Canadian respiratory journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. International Consensus Statement on Obstructive Sleep Apnea.International forum of allergy & rhinology · 2023
    Review
  4. Article
  5. Treatment options in obstructive sleep apnea.Internal and emergency medicine · 2022
    Review
  6. Article
  7. Analysis of risk factors for air leakage in auto-titrating positive airway pressure users: a single-center study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Marius LebretHP2, INSERM U1042, Grenoble Alpes University, Grenoble, France.ORCID 0000-0001-8414-3110
Marie-Caroline RottyIMAG, CNRS, Montpellier University, Montpellier University Hospital, Montpellier, France.
Cyril ArgentoAGIR à dom. Association, Meylan, France.
Jean-Louis PepinHP2, INSERM U1042, Grenoble Alpes University, Grenoble, France.
Renaud TamisierHP2, INSERM U1042, Grenoble Alpes University, Grenoble, France.ORCID 0000-0003-1128-6529
François ArbibCabinet de Pneumologie, Échirolles, France.
Dany JaffuelAPARD Groupe Adène, Montpellier, France.
Nicolas MolinariIMAG, CNRS, Montpellier University, Montpellier University Hospital, Montpellier, France.
Jean-Christian BorelHP2, INSERM U1042, Grenoble Alpes University, Grenoble, France.
Inserm · FRCentre National de la Recherche Scientifique · FRAGIR à dom · FRUniversité de Montpellier · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Auto-CPAP may cause sleep fragmentation due to variations in pressure and unintentional leaks. The aim of this study was to compare air leak between fixed-CPAP and auto-CPAP after 4 months of CPAP treatment. This study is an ancillary analysis of a randomized, double-blind, parallel, controlled trial over 4 months, comparing fixed- and auto-CPAP in newly diagnosed patients with OSA. The following data were extracted from the CPAP devices: mean and 90th percentile pressure, residual apnea-hypopnea index, mean CPAP use, and amount of leak. Within each arm, patients were also randomly allocated to use of one of the three different brands of devices. Since the leak was reported differently for each device, median leak value was determined for each brand and leaks were classified as "above the median" or "below the median". Data from 269 patients were analyzed. The univariate analysis showed that tobacco consumption, CPAP level, and oronasal masks were associated with leaks above the median value but not the type of CPAP. The multivariate analysis showed that only CPAP level and oronasal masks were associated with leaks below the median. There were no differences in the types of mask used between fixed- and auto-CPAP. There was no impact of the type of CPAP on leaks or the type of interface used. We used a method based on the median leak value to standardize comparisons across devices which report leaks with different definitions.

Indexed as

AgedContinuous Positive Airway PressureFemaleHumansMaleMiddle AgedSleep Apnea, Obstructive

Identifiers

PMID31485282
PMCPMC6702837
OpenAlexW2964514364

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.