Evidence map›Paper›PMID 31485251›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2019

Effects of Moxibustion and Moxa Smoke on Behavior Changes and Energy Metabolism in APP/PS1 Mice.

Lue Ha, Mengyun Yu, Zhiyi Yan, Zhang Rui, Baixiao Zhao

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Intranasal essential oils in therapy: advances in clinical applications and delivery mechanisms.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Study on the Multitarget Mechanism and Active Compounds of Essential Oil fromEvidence-based complementary and alternative medicine : eCAM · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Lue HaSchool of Acupuncture, Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing 100029, China.ORCID https://orcid.org/0000-0002-0075-5249
Mengyun YuSchool of Acupuncture, Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing 100029, China.ORCID https://orcid.org/0000-0003-1284-5871
Zhiyi YanSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China.ORCID https://orcid.org/0000-0001-9828-7705
Zhang RuiSchool of Acupuncture, Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing 100029, China.ORCID https://orcid.org/0000-0002-1563-0086
Baixiao ZhaoSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China.ORCID https://orcid.org/0000-0003-3644-6883
Beijing University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the antiaging effects of moxibustion and moxa smoke on APP/PS1 mice and to illustrate the mechanism of moxibustion improving Alzheimer's disease (AD).

methods36 male APP/PS1 mice were randomly assigned into three groups (

resultsIn this study, relative to normal mice, we found that AD mice showed altered tricarboxylic and fatty acid metabolism and showed behavioral changes consistent with the onset of AD. However, both the moxibustion and moxa smoke interventions were able to mitigate these effects to some degree in AD mice.

conclusionsThe data suggest that tricarboxylic acid cycle and unsaturated fatty acid metabolomics changes may be a target of AD, and the beneficial effects of moxibustion on cognitive behaviors may be mediated by the energy metabolism system.

Identifiers

PMID31485251
PMCPMC6710728
OpenAlexW2968593529

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.