Evidence map›Paper›PMID 31485199›Full record

ArticleEnvironmental bioindicators2009

Mercury and Selenium - A Review on Aspects Related to the Health of Human Populations in the Amazon.

Maria da Conceição Nascimento Pinheiro, José Luiz Martins do Nascimento, Luiz Carlos de Lima Silveira, João Batista Teixeira da Rocha, Michael Aschner

Abstract read
In one paragraph

Article in Environmental bioindicators, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 49 citations in OpenAlex.

  1. Influence of theInternational journal of environmental research and public health · 2026
    Article
  2. Article
  3. TheToxics · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Selenium and mercury molar ratios in commercial fish from New Jersey and Illinois: variation within species and relevance to risk communication.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2013
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Oxidative stress in MeHg-induced neurotoxicity.Toxicology and applied pharmacology · 2011
    Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Maria da Conceição Nascimento PinheiroNúcleo de Medicina Tropical, Universidade Federal do Pará, Belém, Pará Brazil.
José Luiz Martins do NascimentoInstituto de Ciências Biológicas, Universidade Federal do Pará, Belém, Pará, Brazil.
Luiz Carlos de Lima SilveiraNúcleo de Medicina Tropical, Universidade Federal do Pará, Belém, Pará Brazil.
João Batista Teixeira da RochaDepartamento de Química, Centro de Ciências Exatas e Naturais, Universidade Federal de Santa Maria, Santa Maria, Brazil.
Michael AschnerDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Universidade Federal do Pará · BRUniversidade Federal de Santa Maria · BRVanderbilt University Medical Center · US

Funding

Mechanisms of Methylmercury Induced Neuron ToxicityR01ES007331 · NIEHS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Michael Aschner, Aaron B Bowman · 1996 to 2026
$10.6M
NIEHS NIH HHS R01 ES007331
6 · The paper itself

Abstract

Mercury (Hg) toxicity is governed by cellular thiol compounds and its capacity to generate reactive oxygen radicals and oxidative stress. Selenium (Se) plays a key role in the prevention of the toxic effects of Hg by modulating the activity of several Se-dependent enzymes, including glutathione peroxidase (GSH-Px). In addition, dietary Se can reduce Hg toxicity by directly interacting with either Hg(II) or methylmercury (MeHg) to form inert products, such as HgSe complexes.. Although experimental and environmental data have indicated a protective role for selenium against Hg toxicity, human data are more limited and somewhat conroversial In the Amazon Region of Brazil, Hg pollution is rampant as a result of gold (Au) mining and other anthropogenic factors, leading to pervasive release of large quantities of metallic Hg

Indexed as

AmazonexposuremercurymethylmercuryseleniumTapajós river basin

Identifiers

PMID31485199
PMCPMC6726406
OpenAlexW2058745260

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.