Evidence map›Paper›PMID 31485016›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2019

Causes of death in preterm neonates (<33 weeks) born in tertiary care hospitals in India: analysis of three large prospective multicentric cohorts.

Kajal Jain, M Jeeva Sankar, Sushma Nangia, Vishnu Bhat Ballambattu, Venkataseshan Sundaram, Siddharth Ramji, Nishad Plakkal, Praveen Kumar, Ashish Jain, Sindhu Sivanandan and 5 more

Abstract readMulticenter Study
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Feasibility of integration of a novel bCPAP system into the NICU of a Public Referral Hospital in Mysuru, India.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  3. Review
  4. Article
  5. ESBL-producingEpidemiology and infection · 2025
    Observational
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Observational
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Kajal JainAll India Institute of Medical Sciences (AIIMS), New Delhi, India.
M Jeeva SankarAll India Institute of Medical Sciences (AIIMS), New Delhi, India.
Sushma NangiaLady Hardinge Medical College (LHMC), New Delhi, India.
Vishnu Bhat BallambattuJawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India.
Venkataseshan SundaramPostgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
Siddharth RamjiMaulana Azad Medical College (MAMC), New Delhi, India.
Nishad PlakkalJawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India.
Praveen KumarPostgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
Ashish JainMaulana Azad Medical College (MAMC), New Delhi, India.
Sindhu SivanandanJawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India.
Sreenivas VishnubhatlaAll India Institute of Medical Sciences (AIIMS), New Delhi, India.
Harish ChellaniVardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
Ashok DeorariAll India Institute of Medical Sciences (AIIMS), New Delhi, India.
Vinod K PaulAll India Institute of Medical Sciences (AIIMS), New Delhi, India.
Ramesh AgarwalAll India Institute of Medical Sciences (AIIMS), New Delhi, India. ra.aiims@gmail.com.

Funding

Wellcome Trust
6 · The paper itself

Abstract

objectiveTo estimate the direct causes of mortality among preterm neonates <33 weeks' gestation by examining three large multisite, hospital-based datasets in India.

methodThree prospective hospital-based datasets: the National Neonatal Perinatal Database (NNPD) of India, the Delhi Neonatal Infection Study (DeNIS) cohort, and the Goat Lung Surfactant Extract (GLSE)-Plus cohort were analyzed to study the causes of death among preterm neonates of less than 33 weeks' gestation admitted to the participating tertiary care hospitals in India.

resultsA total of 8024 preterm neonates were admitted in the three cohorts with 2691 deaths. Prematurity-related complications and sepsis contributed to 53.5% and 19.8% of deaths in the NNPD cohort, 51.0% and 25.0% in the DeNIS cohort, and 39.7% and 40.9% in GLSE-Plus cohort, respectively.

conclusionsNearly a quarter (20-40%) of preterm neonates less than 33 weeks' gestation admitted to Indian NICUs died of sepsis. The study results have implications for health policies targeted to reduce the neonatal mortality rate in India.

Indexed as

Cause of DeathInfant, PrematureHumansIndiaInfantInfant MortalityInfant, NewbornInfant, Premature, DiseasesProspective StudiesSepsisTertiary Care Centers

Identifiers

PMID31485016
PMCPMC8075971

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.