ReviewModern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc2020
Localized malignant mesothelioma, an unusual and poorly characterized neoplasm of serosal origin: best current evidence from the literature and the International Mesothelioma Panel.
Review in Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.
- Primary Intrahepatic Mesothelioma: Case Series and Systematic Review of Literature.Journal of gastrointestinal cancer · 2024Pooled it
- Localised malignant mesothelioma presenting as an esophageal mass: An unusual manifestation.Radiology case reports · 2026Article
- Giant intraparenchymal localized mesothelioma: a rare case report.Irish journal of medical science · 2026Review
- Impact of carbon-based fibers morphologies on their carcinogenic potential.Particle and fibre toxicology · 2026Article
- Cystic epithelioid malignant mesothelioma of the mesentery with rapid postoperative metastasis: an unusual case report.Frontiers in medicine · 2026Article
- The genetics of cancer heterogeneity and mesothelioma.Frontiers in oncology · 2026Review
- Primary Localized Peritoneal Malignant Mesothelioma Involving the Stomach and Transverse Colon: A Case Report.The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2025Article
- Delayed Diagnosis of Peritoneal Mesothelioma in Recurrent Ascites: A Case Report.The American journal of case reports · 2025Article
- A Rare Case of Sarcomatoid-Type Localized Pleural Mesothelioma Derived From Visceral Pleura.Cureus · 2025Article
- Review
- Exploring the histogenesis of STK11 adnexal tumour using electron microscopy.Virchows Archiv : an international journal of pathology · 2024Article
- Clinical outcomes of stereotactic body radiation therapy for malignant pleural mesothelioma.Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2024Article
- Intrapulmonary Biphasic Mesothelioma Misdiagnosed as Adenocarcinoma: Case Report and a Potential Diagnostic Pitfall.OncoTargets and therapy · 2024Article
- Diffuse intrapulmonary mesothelioma mimicking pulmonary lepidic adenocarcinoma: a rare case report and review of the literature.Diagnostic pathology · 2023Review
- Clear-Cell Mesothelioma of Uterine Corpus: Diagnostic Challenges in Intraoperative Frozen Sections.Diagnostics (Basel, Switzerland) · 2023Article
- Localized malignant pleural mesothelioma of the interlobar fissure mimicking a lung cancer.Interactive cardiovascular and thoracic surgery · 2022Article
- Localized malignant mesothelioma in the stomach and mediastinum.Interactive cardiovascular and thoracic surgery · 2022Article
- Solid papillary mesothelial tumor.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2022Article
- When the Diagnosis of Mesothelioma Challenges Textbooks and Guidelines.Journal of clinical medicine · 2021Review
- Diagnostic Challenges in Epithelioid Pleural Mesothelioma: Case Series with Support from Electron Microscopy.Diagnostics (Basel, Switzerland) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
23 authors at 11 institutions in 4 countries.
Funding
Abstract
Localized malignant mesotheliomas (LMM) is an uncommon and poorly recognized neoplasm. Its pathologic diagnosis is often surprising in patients with serosal/subserosal based localized tumors that are clinically suspicious for metastatic lesions or primary sarcomas. Once a tumor is diagnosed as "mesothelioma", LMM is often mistaken for diffuse malignant mesothelioma (DMM). Best currently available evidence about LMM was collected from the literature and cases diagnosed by members of the International Mesothelioma Panel (IMP). One hundred and one (101) LMM have been reported in the English literature. Patients had localized tumors with identical histopathologic features to DMM. Patients ranged in age from 6 to 82 years; 75% were men. Most (82%) of the tumors were intrathoracic. Others presented as intrahepatic, mesenteric, gastric, pancreatic, umbilical, splenic, and abdominal wall lesions. Tumors varied in size from 0.6 to 15 cm. Most patients underwent surgical resection and/or chemotherapy or radiation therapy. Median survival in a subset of patients was 29 months. Seventy two additional LMM from IMP institutions ranged in age from 28 to 95 years; 58.3% were men. Sixty tumors (83.3%) were intrathoracic, others presented in intraabdominal sites. Tumors varied in size from 1.2 to 19 cm. Median survival for 51 cases was 134 months. Best evidence was used to formulate guidelines for the diagnosis of LMM. It is important to distinguish LMM from DMM as their treatment and prognosis is different. A multidisciplinary approach is needed for the diagnosis of LMM as it shows identical histopathology and immunophenotype to DMM.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.