Evidence map›Paper›PMID 31484905›Full record

ArticleInternal medicine (Tokyo, Japan)2020

Oryeongsan (Goreisan) Ameliorates Experimental Autoimmune Encephalomyelitis.

Rino Inada, Katsuichi Miyamoto, Noriko Tanaka, Kota Moriguchi, Susumu Kusunoki

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Rino InadaDepartment of Neurology, Kindai University School of Medicine, Japan.
Katsuichi MiyamotoDepartment of Neurology, Kindai University School of Medicine, Japan.
Noriko TanakaDepartment of Neurology, Kindai University School of Medicine, Japan.
Kota MoriguchiDepartment of Neurology, Kindai University School of Medicine, Japan.
Susumu KusunokiDepartment of Neurology, Kindai University School of Medicine, Japan.
Kindai University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective Oryeongsan (Goreisan), a formula composed of five herbal medicines, has long been used to treat impairments of the regulation of body fluid homeostasis. Goreisan has been revealed to have anti-inflammatory actions and inhibit a water channel, the aquaporin (AQP). We herein report the therapeutic effect of Goreisan on experimental autoimmune encephalomyelitis (EAE in, an animal model of inflammatory demyelinating diseases. Materials and Methods EAE mice immunized with MOG

Indexed as

AnimalsAquaporin 4CD4-Positive T-LymphocytesCell ProliferationCentral Nervous SystemCytokinesDisease Models, AnimalDrugs, Chinese HerbalEncephalomyelitis, Autoimmune, ExperimentalFemaleHumansMiceMice, Inbred C57BLRNA, MessengerSpinal CordAqp4 protein, mouseAquaporin 4CytokinesDrugs, Chinese HerbaloryeongsanRNA, Messengeraquaporinexperimental autoimmune encephalomyelitisGoreisanherbal medicinemultiple sclerosisOryeongsan

Identifiers

PMID31484905
PMCPMC6995709
OpenAlexW2971824319

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.