Evidence map›Paper›PMID 31484849›Full record

ArticleMagnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine2020

Deep Learning Based Noise Reduction for Brain MR Imaging: Tests on Phantoms and Healthy Volunteers.

Masafumi Kidoh, Kensuke Shinoda, Mika Kitajima, Kenzo Isogawa, Masahito Nambu, Hiroyuki Uetani, Kosuke Morita, Takeshi Nakaura, Machiko Tateishi, Yuichi Yamashita and 1 more

Abstract read
In one paragraph

Article in Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 125 papers.

0numbers the graph read from it
0cells of the map it votes in
125citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

125 citing papers in PubMed.

  1. Fast Submillimeter Whole-Brain TMagnetic resonance in medicine · 2026
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  7. A Novel MR Cine Sialography Technique for Evaluating Salivary Gland Function: Correlation with Unstimulated and Stimulated Saliva Volumes.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2026
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  10. Accelerating imaging: deep learning for enhancedJapanese journal of radiology · 2026
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  11. Visualization of the Trochlear Nerve Using Deep Learning-enhanced 3D T2-weighted MR Imaging at 3T.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2026
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  15. Visualization of the Eustachian Tube Cartilage on Delayed Contrast-enhanced 3D-MR Imaging: A Preliminary Comparison between Ionic and Non-ionic Gadolinium-based Contrast Agents.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2026
    Article
  16. Article
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  18. Effects of Artificial Intelligence-based Reconstruction on Image Quality and Voxel-based Morphometry Analysis of Atrophy in Accelerated MPRAGE.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2026
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  19. Article
  20. Article

65 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Masafumi KidohDepartment of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University.
Kensuke ShinodaMRI Systems Division, Canon Medical Systems Corporation.
Mika KitajimaDepartment of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University.
Kenzo IsogawaCorporate Research and Development Center, Toshiba Corporation.
Masahito NambuMRI Systems Division, Canon Medical Systems Corporation.
Hiroyuki UetaniDepartment of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University.
Kosuke MoritaDepartment of Radiology, Kumamoto University Hospital, Kumamoto.
Takeshi NakauraDepartment of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University.
Machiko TateishiDepartment of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University.
Yuichi YamashitaMRI Systems Division, Canon Medical Systems Corporation.
Yasuyuki YamashitaDepartment of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo test whether our proposed denoising approach with deep learning-based reconstruction (dDLR) can effectively denoise brain MR images.

methodsIn an initial experimental study, we obtained brain images from five volunteers and added different artificial noise levels. Denoising was applied to the modified images using a denoising convolutional neural network (DnCNN), a shrinkage convolutional neural network (SCNN), and dDLR. Using these brain MR images, we compared the structural similarity (SSIM) index and peak signal-to-noise ratio (PSNR) between the three denoising methods. Two neuroradiologists assessed the image quality of the three types of images. In the clinical study, we evaluated the denoising effect of dDLR in brain images with different levels of actual noise such as thermal noise. Specifically, we obtained 2D-T

resultsIn the experimental study, PSNR and SSIM for dDLR were statistically higher than those of DnCNN and SCNN (P < 0.001). The image quality of dDLR was also superior to DnCNN and SCNN. In the clinical study, dDLR-NAQ2 was significantly better than NAQ2 images for SSIM and PSNR in all three sequences (P < 0.05), except for PSNR in FLAIR. For all qualitative items, dDLR-NAQ2 had equivalent or better image quality than NAQ5, and superior quality to that of NAQ2 (P < 0.05), for all criteria except artifact. The inter-observer agreement ranged from substantial to near perfect.

conclusiondDLR reduces image noise while preserving image quality on brain MR images.

Indexed as

Deep LearningBrainHumansImage Interpretation, Computer-AssistedMagnetic Resonance ImagingPhantoms, ImagingSignal-To-Noise Ratiobrain magnetic resonance imagingdeep learning convolutional neural networkimage reconstructionnoise reduction

Identifiers

PMID31484849
PMCPMC7553817

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.