Evidence map›Paper›PMID 31484796›Full record

ArticleBioscience reports2019

Mesenchymal stem cells significantly improved treatment effects of Linezolid on severe pneumonia in a rabbit model.

Dexiao Kong, Xia Liu, Xiaomei Li, Jianting Hu, Xiaoyan Li, Juan Xiao, Yibo Dai, Mingming He, Xiaoli Liu, Yang Jiang and 9 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioscience reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 4 institutions in 1 country.

Dexiao KongDepartment of hematology of the Second Hospital, Institute of Biotherapy for Hematological Malignancies, Shandong University-Karolinska Institute Collaborative Laboratory for Stem Cell Research, Shandong University, Jinan, Shandong Province, China.
Xia LiuDepartment of Respiratory Intervention, Qilu Children's Hospital of Shandong University, Jinan, Shandong Province, China.
Xiaomei LiCancer Center, The Second Hospital of Shandong University, Jinan, Shandong Province, China.
Jianting HuShandong Pharmaceutical Academy, Shandong Provincial Key Laboratory of Chemical Drugs, Jinan, Shandong Province, China.
Xiaoyan LiDepartment of hematology of the Second Hospital, Institute of Biotherapy for Hematological Malignancies, Shandong University-Karolinska Institute Collaborative Laboratory for Stem Cell Research, Shandong University, Jinan, Shandong Province, China.
Juan XiaoDepartment of hematology of the Second Hospital, Institute of Biotherapy for Hematological Malignancies, Shandong University-Karolinska Institute Collaborative Laboratory for Stem Cell Research, Shandong University, Jinan, Shandong Province, China.
Yibo DaiDepartment of hematology of the Second Hospital, Institute of Biotherapy for Hematological Malignancies, Shandong University-Karolinska Institute Collaborative Laboratory for Stem Cell Research, Shandong University, Jinan, Shandong Province, China.
Mingming HeDepartment of hematology of the Second Hospital, Institute of Biotherapy for Hematological Malignancies, Shandong University-Karolinska Institute Collaborative Laboratory for Stem Cell Research, Shandong University, Jinan, Shandong Province, China.
Xiaoli LiuDepartment of hematology of the Second Hospital, Institute of Biotherapy for Hematological Malignancies, Shandong University-Karolinska Institute Collaborative Laboratory for Stem Cell Research, Shandong University, Jinan, Shandong Province, China.
Yang JiangDepartment of hematology of the Second Hospital, Institute of Biotherapy for Hematological Malignancies, Shandong University-Karolinska Institute Collaborative Laboratory for Stem Cell Research, Shandong University, Jinan, Shandong Province, China.
Ruodi CuiDepartment of Radiology, Qilu Children's Hospital of Shandong University, Jinan, Shandong Province, China.
Lihong ZhangDepartment of Pathology, Qilu Children's Hospital of Shandong University, Jinan, Shandong Province, China.
Juandong WangDepartment of hematology of the Second Hospital, Institute of Biotherapy for Hematological Malignancies, Shandong University-Karolinska Institute Collaborative Laboratory for Stem Cell Research, Shandong University, Jinan, Shandong Province, China.
Ai LiDepartment of hematology of the Second Hospital, Institute of Biotherapy for Hematological Malignancies, Shandong University-Karolinska Institute Collaborative Laboratory for Stem Cell Research, Shandong University, Jinan, Shandong Province, China.
Fang WangClinical Laboratory, The Second Hospital of Shandong University, Jinan, Shandong Province, China.
Yuan ZhangCenter of Evidence-Based Medicine, The Second Hospital of Shandong University, Jinan, Shandong Province, China.
Juan XiaoCenter of Evidence-Based Medicine, The Second Hospital of Shandong University, Jinan, Shandong Province, China.
Wei WangDepartment of Respiratory Medicine, The Second Hospital of Shandong University, Jinan, Shandong Province, China cyzheng2016@126.com weumwc@sina.com.
Chengyun ZhengDepartment of hematology of the Second Hospital, Institute of Biotherapy for Hematological Malignancies, Shandong University-Karolinska Institute Collaborative Laboratory for Stem Cell Research, Shandong University, Jinan, Shandong Province, China cyzheng2016@126.com weumwc@sina.com.ORCID 0000-0003-3310-2292
Shandong University · CNSecond Hospital of Shandong University · CNQilu Hospital of Shandong University · CNShandong Academy of Pharmaceutical Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study aimed to investigate whether co-administration of mesenchymal stromal cells (MSC) and linezolid (LZD) into a rabbit model of methicillin-resistant

Indexed as

Mesenchymal Stem Cell TransplantationAnimalsAnti-Bacterial AgentsCells, CulturedCombined Modality TherapyCytokinesDisease Models, AnimalHumansLinezolidLungMaleMesenchymal Stem CellsMethicillin-Resistant Staphylococcus aureusNeutrophilsPneumonia, StaphylococcalRabbitsAnti-Bacterial AgentsCytokinesLinezolidlinezolidMesenchymal stem cellsMRSArabbit modelStaphylococcus aureussynergistic effect

Identifiers

PMID31484796
PMCPMC6746999
OpenAlexW2971563858

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.