Evidence map›Paper›PMID 31484763›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Extreme heterogeneity in sex chromosome differentiation and dosage compensation in livebearers.

Iulia Darolti, Alison E Wright, Benjamin A Sandkam, Jake Morris, Natasha I Bloch, Marta Farré, Rebecca C Fuller, Godfrey R Bourne, Denis M Larkin, Felix Breden and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed
10.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 107 citations in OpenAlex.

  1. Article
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  4. Ancestral gene flow shaped the singular origin of the Amazon molly.bioRxiv : the preprint server for biology · 2026
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  13. Sharks and rays have the oldest vertebrate sex chromosome with unique sex determination mechanisms.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Sex Chromosome Evolution: Hallmarks and Question Marks.Molecular biology and evolution · 2024
    Review

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 10 institutions in 5 countries.

Iulia DaroltiDepartment of Genetics, Evolution and Environment, University College London, London WC1E 6BT, United Kingdom; iulia.darolti.15@ucl.ac.uk.
Alison E WrightDepartment of Animal and Plant Sciences, University of Sheffield, Sheffield S10 2TN, United Kingdom.
Benjamin A SandkamDepartment of Zoology, University of British Columbia, Vancouver, BC V6T 1Z4, Canada.ORCID 0000-0002-5043-9295
Jake MorrisDepartment of Genetics, Evolution and Environment, University College London, London WC1E 6BT, United Kingdom.
Natasha I BlochDepartment of Biomedical Engineering, University of Los Andes, Bogotá 111711, Colombia.
Marta FarréSchool of Biosciences, University of Kent, Canterbury CT2 7NJ, United Kingdom.
Rebecca C FullerDepartment of Animal Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801.
Godfrey R BourneDepartment of Biology, University of Missouri-St. Louis, St. Louis, MO 63105.
Denis M LarkinDepartment of Comparative Biomedical Sciences, Royal Veterinary College, London NW1 0TU, United Kingdom.
Felix BredenDepartment of Biological Science, Simon Fraser University, Burnaby, BC V5A 1S6, Canada.
Judith E MankDepartment of Genetics, Evolution and Environment, University College London, London WC1E 6BT, United Kingdom.
University College London · GBRoyal Veterinary College · GBSimon Fraser University · CAUniversidad de Los Andes · COUniversity of British Columbia · CAUniversity of Illinois Urbana-Champaign · USUniversity of Kent · GBUniversity of Missouri–St. Louis · USUniversity of Sheffield · GBUppsala University · SE

Funding

Biotechnology and Biological Sciences Research Council BB/M009513/1
6 · The paper itself

Abstract

Once recombination is halted between the X and Y chromosomes, sex chromosomes begin to differentiate and transition to heteromorphism. While there is a remarkable variation across clades in the degree of sex chromosome divergence, far less is known about the variation in sex chromosome differentiation within clades. Here, we combined whole-genome and transcriptome sequencing data to characterize the structure and conservation of sex chromosome systems across Poeciliidae, the livebearing clade that includes guppies. We found that the

Indexed as

Dosage Compensation, GeneticGenes, X-LinkedGenetic VariationGenomeSex DifferentiationAnimalsEvolution, MolecularFemaleMalePoeciliaSex ChromosomesTranscriptomedosage compensationpoeciliidsrecombinationY degeneration

Identifiers

PMID31484763
PMCPMC6754558
OpenAlexW2971903263

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.