Evidence map›Paper›PMID 31484721›Full record

ArticleThe Journal of biological chemistry2019

Evolutionary plasticity in the allosteric regulator-binding site of pyruvate kinase isoform PykA from

Yassmin Abdelhamid, Paul Brear, Jack Greenhalgh, Xavier Chee, Taufiq Rahman, Martin Welch

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. An allantoin-inducible glyoxylate utilization pathway inMicrobiology (Reading, England) · 2025
    Article
  2. Article
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  5. Review
  6. Article
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  8. The KInternational journal of molecular sciences · 2022
    Article
  9. The methylation-independent mismatch repair machinery inMicrobiology (Reading, England) · 2021
    Review
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yassmin AbdelhamidDepartment of Biochemistry, University of Cambridge, Cambridge CB2 1QW, United Kingdom.ORCID 0000-0003-0548-158X
Paul BrearDepartment of Biochemistry, University of Cambridge, Cambridge CB2 1QW, United Kingdom.ORCID 0000-0002-4045-0474
Jack GreenhalghDepartment of Pharmacology, University of Cambridge, Cambridge CB2 1PD, United Kingdom.
Xavier CheeDepartment of Pharmacology, University of Cambridge, Cambridge CB2 1PD, United Kingdom.
Taufiq RahmanDepartment of Pharmacology, University of Cambridge, Cambridge CB2 1PD, United Kingdom.ORCID 0000-0003-3830-5160
Martin WelchDepartment of Biochemistry, University of Cambridge, Cambridge CB2 1QW, United Kingdom. mw240@cam.ac.uk.ORCID 0000-0003-3646-1733
University of Cambridge · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Unlike many other well-characterized bacteria, the opportunistic human pathogen

Indexed as

Allosteric RegulationAllosteric SiteBacterial ProteinsCatalytic DomainGlucose-6-PhosphateIsoenzymesModels, MolecularPentose Phosphate PathwayPseudomonas aeruginosaPyruvate KinaseBacterial ProteinsGlucose-6-PhosphateIsoenzymesPyruvate Kinaseallosterybacterial metabolismEntner-Doudoroff Pathwayglycolysispentose phosphate pathway (PPP)PseudomonasPseudomonas aeruginosaPykApyruvate kinaseX-ray crystallography

Identifiers

PMID31484721
PMCPMC6802521
OpenAlexW2972238193

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.