Evidence map›Paper›PMID 31484696›Full record

Trial reportJournal of lipid research2019

Four nights of sleep restriction suppress the postprandial lipemic response and decrease satiety.

Kelly M Ness, Stephen M Strayer, Nicole G Nahmod, Margeaux M Schade, Anne-Marie Chang, Gregory C Shearer, Orfeu M Buxton

Open access · hybridAbstract readClinical Trial
In one paragraph

Trial report in Journal of lipid research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Kelly M NessHuck Institutes of the Life Sciences, Pennsylvania State University, University Park, PA 16802.ORCID 0000-0002-3889-7939
Stephen M StrayerHuck Institutes of the Life Sciences, Pennsylvania State University, University Park, PA 16802.
Nicole G NahmodDepartments of Biobehavioral Health Pennsylvania State University, University Park, PA 16802.
Margeaux M SchadeDepartments of Biobehavioral Health Pennsylvania State University, University Park, PA 16802.
Anne-Marie ChangHuck Institutes of the Life Sciences, Pennsylvania State University, University Park, PA 16802.
Gregory C ShearerHuck Institutes of the Life Sciences, Pennsylvania State University, University Park, PA 16802.ORCID 0000-0003-4722-9163
Orfeu M BuxtonHuck Institutes of the Life Sciences, Pennsylvania State University, University Park, PA 16802 orfeu@psu.edu.ORCID 0000-0001-5057-633X
Pennsylvania State University · USBrigham and Women's Hospital · US

Funding

Penn State Clinical and Translational Science InstituteUL1TR002014 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI KRASCHNEWSKI, JENNIFER L. · 2016 to 2025
$33.7M
Research Training in Physiological Adaptations to StressT32GM108563 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI CANTORNA, MARGHERITA T, KORZICK, DONNA HOPE · 2014 to 2023
$2.2M
Non-pharmacological improvement of sleep structure in older peopleR43AG056250 · NIA · MOBILE SLEEP TECHNOLOGIES, LLC · PI GARTENBERG, DANIEL, GERASHCHENKO, DMITRY · 2017 to 2018
$696k
NCATS NIH HHS UL1 TR002014NIA NIH HHS R43 AG056250NIGMS NIH HHS T32 GM108563
6 · The paper itself

Abstract

Chronic sleep restriction, or inadequate sleep, is associated with increased risk of cardiometabolic disease. Laboratory studies demonstrate that sleep restriction causes impaired whole-body insulin sensitivity and glucose disposal. Evidence suggests that inadequate sleep also impairs adipose tissue insulin sensitivity and the NEFA rebound during intravenous glucose tolerance tests, yet no studies have examined the effects of sleep restriction on high-fat meal lipemia. We assessed the effect of 5 h time in bed (TIB) per night for four consecutive nights on postprandial lipemia following a standardized high-fat dinner (HFD). Furthermore, we assessed whether one night of recovery sleep (10 h TIB) was sufficient to restore postprandial metabolism to baseline. We found that postprandial triglyceride (TG) area under the curve was suppressed by sleep restriction (

Indexed as

Postprandial PeriodSatiationAdipocytesAdultBlood GlucoseGlucose Tolerance TestHumansHyperlipidemiasMaleSleep DeprivationTriglyceridesYoung AdultBlood GlucoseTriglyceridesdiet and dietary lipidsfatty acidglucosehormonesinflammationinsulin resistancelipolysis and fatty acid metabolismnutritiontriglycerides

Identifiers

PMID31484696
PMCPMC6824500
OpenAlexW2971434848

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.