Evidence map›Paper›PMID 31484661›Full record

ArticleBMJ health & care informatics2019

Combined effect of pill refilling and self-medication reminder system on patients' adherence to tuberculosis treatment during continuation phase in Northwest Ethiopia: a study protocol for randomised controlled trial.

Kassahun Dessie Gashu, Kassahun Alemu Gelaye, Richard Lester, Binyam Tilahun

Open access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in BMJ health & care informatics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Kassahun Dessie GashuUniversity of Gondar, College of Medicine and Health Sciences, Institute of Public Health, Gondar, Ethiopia kassahundessie@gmail.com.ORCID http://orcid.org/0000-0002-7812-3743
Kassahun Alemu GelayeUniversity of Gondar, College of Medicine and Health Sciences, Institute of Public Health, Gondar, Ethiopia.
Richard LesterUniversity of British Columbia, Research Pavilion, Rm 566, 828 W 10th, Vancouver, BC, V5Z 1 M9, Canada.
Binyam TilahunUniversity of Gondar, College of Medicine and Health Sciences, Institute of Public Health, Gondar, Ethiopia.
University of Gondar · ETUniversity of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPatients' failure to adhere on tuberculosis (TB) treatment leads to drug resistance, relapse and death. Non-adherence to TB treatment is higher during continuation treatment phase. The study aimed to evaluate effectiveness of combined pill refilling and medication reminders on adherence to TB treatment. METHODS AND ANALYSIS: A two-arm randomised controlled trial on adult patients with TB was used during continuation treatment phase. In the first arm, in addition to usual care, participants will receive cellphone-based daily medication and weekly pill refilling reminders. In the control arm, participants will receive only usual care. The study will use a covariate adaptive randomisation technique to balance covariates during allocation. The primary outcome is patients' adherence to TB treatment and secondary outcomes are attendance to clinic and treatment outcomes. We apply intention to treat with generalised linear mixed model. ETHICS AND DISSEMINATION: Ethical approval was obtained from Institutional Review Board of University of Gondar. Written informed consent was applied during enrolment. We will publish findings in peer-reviewed, scientific journals and conferences. TRIAL REGISTRATION NUMBER: PACTR201901552202539.

Indexed as

Medication AdherenceReminder SystemsText MessagingAdultAntitubercular AgentsCell PhoneEthiopiaFemaleHumansMaleRandomized Controlled Trials as TopicTreatment OutcomeTuberculosisAntitubercular Agentspatient appointmentshort message servicetreatment adherencetreatment outcome

Identifiers

PMID31484661
PMCPMC7062340
OpenAlexW2977801923

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.