ArticleThe British journal of ophthalmology2020
Five-year changes in anterior segment parameters in an older population in urban southern China: the Liwan Eye Study.
Article in The British journal of ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Ocular Biometric Risk Factors for Progression of Primary Angle Closure Disease: The Zhongshan Angle Closure Prevention Trial.Ophthalmology · 2022Trial
- Effect of mydriasis on anterior segment biometric parameters of patients with age-related cataracts.BMC ophthalmology · 2025Article
- The Effect of Physical Activity on Anterior Segment Structures and the Retinal Nerve Fiber Layer: A Comparison of Elite Athletes and Sedentary Individuals.Medicina (Kaunas, Lithuania) · 2025Observational
- Risk factor stratification in early-onset primary angle closure disease.Eye (London, England) · 2025Observational
- Article
- Ocular Biometry of Primary Angle-Closure Disease in Younger Patients.Frontiers in medicine · 2021Article
- Intradevice Repeatability and Interdevice Agreement of Ocular Biometric Measurements: A Comparison of Two Swept-Source Anterior Segment OCT Devices.Translational vision science & technology · 2020Article
- Anterior Segment OCT for Detection of Narrow Angles: A Community-Based Diagnostic Accuracy Study.Ophthalmology. GlaucomaArticle
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Authors and funding
9 authors.
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Abstract
purposeTo investigate the 5-year changes in static and dynamic anterior segment optical coherence tomography (AS-OCT) parameters and their predictors.
methodsThis was a prospective, population-based cohort study of people aged 50 years and older residing in the Liwan District, Guangzhou, China. Standardised AS-OCT scans were performed in November 2008 and November 2013 under dark and light conditions. Customised software was used to analyse horizontal AS-OCT images. Parameters in dark and measurements of light-to-dark changes were used for analyses.
resultsA total of 186 (71.8%) subjects underwent AS-OCT twice, 5 years apart and were included for analyses. The mean age in 2008 was 64.7±7.0 years, and 60.2% were women. The anterior chamber width (ACW) decreased from 11.74±0.44 mm in 2008 to 11.60±0.37 mm in 2013 (p=0.001). There was a trend towards a decrease in dynamic capacity (light-to-dark changes) in the anterior segment, with decreased iris thickness at 750 µm (ΔIT750), ΔACW, Δ anterior chamber area (ACA) and Δ pupil diameter at 5 years (all p<0.05). After adjusting for age and sex, the following baseline parameters were associated with a greater decrease rate in trabecular iris space area at 500 µm (TISA500) at 5 years: TISA500, IT750 and ACA in dark (p<0.001 for all).
conclusionsAnterior chamber angle width decreased and the amount of light-to-dark changes declined during 5-year follow-up. Subjects with greater height, wider angle width and thicker iris at baseline have greater angle narrowing at follow-up.
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