ArticleBMC musculoskeletal disorders2019
Does peak bone mass correlate with peak bone strength? Cross-sectional normative dual energy X-ray absorptiometry data in 1052 men aged 18-28 years.
Article in BMC musculoskeletal disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Variations over time in proximal femoral strength in young adult men are not explained by areal bone mineral density alone.JBMR plus · 2025Article
- High-Intensity Physical Activity During Late Adolescence Predicts Young Adult CT-Based Finite Element Bone Strength in Emerging Adulthood: Iowa Bone Development Study.Children (Basel, Switzerland) · 2025Article
- Associations Between Youth Sport Participation and Bone, Muscle, and Fat in Adulthood: Iowa Bone Development Study.International journal of environmental research and public health · 2025Article
- A Comprehensive Analysis of Bone Mineral Density Changes across the Lifespan: Insights from National Surveys.Nutrients · 2024Article
- Acquisition of peak bone mass in a Norwegian youth cohort: longitudinal findings from the Fit Futures study 2010-2022.Archives of osteoporosis · 2024Article
- Peak Bone Mass Formation: Modern View of the Problem.Biomedicines · 2023Review
- Bone mineral density and muscle mass in adults with developmental skeletal discrepancies.BMC musculoskeletal disorders · 2022Article
- Exercise and Peak Bone Mass.Current osteoporosis reports · 2020Review
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Authors and funding
3 authors.
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Abstract
backgroundAreal bone mineral density (aBMD) estimated by dual-energy X-ray absorptiometry (DXA) is used to estimate peak bone mass, define osteoporosis and predict fracture. However, as aBMD is calculated as bone mineral content (BMC) divided by the scanned area, aBMD displays an inverse relationship with bone size. In a skeleton that is increasing in size, this is a problem, as bone size is an independent factor that determines bone strength. It could therefore be questioned whether peak aBMD is the period with greatest bone strength, a period that in the hip then would occur in ages 16-19. The aim of this study was to evaluate whether there are changes in bone size in men after age 18 that may influence peak bone strength. Another aim was to provide updated normative DXA data.
methodsWe scanned left femoral neck by DXA in a cross-sectional study with a population-based selection of 1052 men aged 18-28, and then registered bone mineral content (BMC, gram), aBMD (gram/cm
resultsWe found the highest absolute femoral neck aBMD at age 19, with statistically significant differences between the one-year age groups in BMC, aBMD, and bone area (all p < 0.05). From peak bone mass onwards (n = 962), there are negative correlations between age and BMC (r = - 0.07; p < 0.05) and age and aBMD (r = - 0.12; p < 0.001), and positive correlation between age and bone area (r = 0.06; p < 0.05).
conclusionAs femoral neck bone size in young adult men becomes larger after peak bone mass, it could be questioned whether DXA estimated peak aBMD correlates with peak bone strength. We infer that aBMD must be interpreted with care in individuals with a growing skeleton, since skeletal strength may then increase, in spite of decreasing aBMD. This should be taken into account when performing DXA measurements in these ages.
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