Evidence map›Paper›PMID 31484392›Full record

ArticleInternational journal of molecular sciences2019

Impact of Chronic BDNF Depletion on GABAergic Synaptic Transmission in the Lateral Amygdala.

Susanne Meis, Thomas Endres, Thomas Munsch, Volkmar Lessmann

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Modified human mesenchymal stromal/stem cells restore cortical excitability after focal ischemic stroke in rats.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Susanne MeisInstitut für Physiologie, Otto-von-Guericke-Universität, D-39120 Magdeburg, Germany. susanne.meis@med.ovgu.de.
Thomas EndresInstitut für Physiologie, Otto-von-Guericke-Universität, D-39120 Magdeburg, Germany. thomas.endres@med.ovgu.de.ORCID 0000-0003-4263-2922
Thomas MunschInstitut für Physiologie, Otto-von-Guericke-Universität, D-39120 Magdeburg, Germany. thomas.munsch@med.ovgu.de.
Volkmar LessmannInstitut für Physiologie, Otto-von-Guericke-Universität, D-39120 Magdeburg, Germany. lessmann@med.ovgu.de.ORCID 0000-0002-6863-323X
Center for Behavioral Brain Sciences · DEOtto-von-Guericke-Universität Magdeburg · DE

Funding

Deutsche Forschungsgemeinschaft SFB 779 TP B6EU Joint Programme Neurodegenerative Disease Research (JPND): CIRCPROT
6 · The paper itself

Abstract

Brain-derived neurotrophic factor (BDNF) has previously been shown to play an important role in glutamatergic synaptic plasticity in the amygdala, correlating with cued fear learning. While glutamatergic neurotransmission is facilitated by BDNF signaling in the amygdala, its mechanism of action at inhibitory synapses in this nucleus is far less understood. We therefore analyzed the impact of chronic BDNF depletion on GABA

Indexed as

AmygdalaAnimalsBrain-Derived Neurotrophic FactorFemalegamma-Aminobutyric AcidLong-Term PotentiationMiceMice, KnockoutNeuronal PlasticityPatch-Clamp TechniquesSynaptic TransmissionBrain-Derived Neurotrophic Factorgamma-Aminobutyric AcidamygdalaBDNFGABAheterozygous BDNF knockout miceLTP

Identifiers

PMID31484392
PMCPMC6747405
OpenAlexW2971573623

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.