Evidence map›Paper›PMID 31484389›Full record

ArticlePharmaceutics2019

Increased Efficacy of Oral Fixed-Dose Combination of Amphotericin B and AHCC

Alba Pérez-Cantero, Dolores R Serrano, Patricia Navarro-Rodríguez, Andreas G Schätzlein, Ijeoma F Uchegbu, Juan J Torrado, Javier Capilla

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
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  5. The Pathogenesis ofPolish journal of microbiology · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Alba Pérez-CanteroUnitat de Microbiologia, Facultat de Medicina i Ciències de la Salut, Universitat Rovira i Virgili and Institut d'Investigació Sanitària Pere Virgili (IISPV), 43201 Reus, Tarragona, Spain.ORCID 0000-0001-9238-5849
Dolores R SerranoDepartament of Pharmaceutics and Food Technology and Instituto Universitario de Farmacia Industrial (IUFI), School of Pharmacy, University Complutense, Avenida Complutense, 28040 Madrid, Spain.ORCID 0000-0002-0475-8420
Patricia Navarro-RodríguezUnitat de Microbiologia, Facultat de Medicina i Ciències de la Salut, Universitat Rovira i Virgili and Institut d'Investigació Sanitària Pere Virgili (IISPV), 43201 Reus, Tarragona, Spain.
Andreas G SchätzleinNanomerics Ltd., St. Albans AL1 1SR, UK.ORCID 0000-0003-3907-6603
Ijeoma F UchegbuUCL School of Pharmacy, 29-39, Brunswick Square, London WC1N 1AX, UK.
Juan J TorradoDepartament of Pharmaceutics and Food Technology and Instituto Universitario de Farmacia Industrial (IUFI), School of Pharmacy, University Complutense, Avenida Complutense, 28040 Madrid, Spain.
Javier CapillaUnitat de Microbiologia, Facultat de Medicina i Ciències de la Salut, Universitat Rovira i Virgili and Institut d'Investigació Sanitària Pere Virgili (IISPV), 43201 Reus, Tarragona, Spain. javier.capilla@urv.cat.ORCID 0000-0002-0765-6403
Institut de Recerca Biomèdica Catalunya Sud · ESUniversidad Complutense de Madrid · ESPsychometric Research & Development (United Kingdom) · GBUniversity College London · GB

Funding

Universidad Complutense de Madrid 910939
6 · The paper itself

Abstract

Invasive pulmonary aspergillosis represents one of the most serious fungal infections among immunocompromised patients. In this study, we aimed to analyze the in vivo efficacy of prophylactic oral amphotericin B (AMB) encapsulated in modified chitosan-nanoparticles (Nanomerics' Molecular Envelope Technology (MET)) supplemented with a standardized extract of cultured

Indexed as

AHCC®amphotericin BaspergillosischitosanLentinula edodesMolecular Envelope Technologyoral deliveryshiitake

Identifiers

PMID31484389
PMCPMC6781303
OpenAlexW2971973725

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.