Evidence map›Paper›PMID 31484365›Full record

ArticleToxins2019

Molecular Determinants of Brevetoxin Binding to Voltage-Gated Sodium Channels.

Keiichi Konoki, Daniel G Baden, Todd Scheuer, William A Catterall

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Keiichi KonokiDepartment of Pharmacology, Box 357280, University of Washington, Seattle, WA 98195-7280, USA. keiichi.konoki.b2@tohoku.ac.jp.ORCID 0000-0001-5788-5426
Daniel G BadenCenter for Marine Science, University of North Carolina, Wilmington, NC 28409, USA.
Todd ScheuerDepartment of Pharmacology, Box 357280, University of Washington, Seattle, WA 98195-7280, USA.ORCID 0000-0003-3655-0816
William A CatterallDepartment of Pharmacology, Box 357280, University of Washington, Seattle, WA 98195-7280, USA. wcatt@uw.edu.
University of Washington · USUniversity of North Carolina Wilmington · US

Funding

Intellectual and Developmental Disabilities Research CenterU54HD083091 · NICHD · UNIVERSITY OF WASHINGTON · PI DOHERTY, DANIEL · 2014 to 2019
$7.9M
Sodium and Calcium Channels: Structure, Function, Neuroplasticity, and DiseaseR35NS111573 · NINDS · UNIVERSITY OF WASHINGTON · PI SCOTT, JOHN D · 2019 to 2024
$6.1M
VOLTAGE-SENSITIVE SODIUM CHANNELS IN BRAINR01NS015751 · NINDS · UNIVERSITY OF WASHINGTON · PI CATTERALL, WILLIAM A · 1985 to 2018
$6.0M
NICHD NIH HHS U54 HD083091NIH HHS R-01 N515751NINDS NIH HHS R01 NS015751NINDS NIH HHS R35 NS111573
6 · The paper itself

Abstract

Brevetoxins are produced by dinoflagellates such as

Indexed as

Binding SitesCell LineHumansMarine ToxinsMutationOxocinsPolyether ToxinsProtein IsoformsVoltage-Gated Sodium ChannelsbrevetoxinMarine ToxinsOxocinsPolyether ToxinsProtein IsoformsVoltage-Gated Sodium Channelsbinding assayneurotoxic shellfish poisoningvoltage-gated sodium channels

Identifiers

PMID31484365
PMCPMC6784055
OpenAlexW2971958495

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.